Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8669502 | 0.98 | TDP1 (0.67) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL28639312 | 0.90 | RAB9A (0.56) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL19866979 | 0.88 | KMT2A (0.82) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL312910 | 0.88 | TDP1 (0.81) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL4993714 | 0.87 | TDP1 (0.68) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL12856431 | 0.87 | TDP1 (0.68) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL8761237 | 0.84 | TDP1 (0.69) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL6163969 | 0.84 | TDP1 (0.69) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL27395893 | 0.84 | TDP1 (0.69) | TDP1KMT2ASLC6A2SLC6A3RAB9A | |
| SCHEMBL181934 | 0.83 | TDP1 (0.73) | TDP1KMT2ASLC6A2SLC6A3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203003-A1 | Notch Inhibitors and Uses Thereof | STEMSYNERGY THERAPEUTICS, INC. | 2023-06-29 | — | — | US | disclosed |
| US-11214538-B2 | Farnesoid X receptor agonists and uses thereof | METACRINE, INC. (US) | 2022-01-04 | — | — | US | disclosed |
| EP-3353152-B1 | METHOD | NORSK MEDISINSK SYKLOTRONSENTER AS (NO) | 2021-09-15 | — | — | EP | disclosed |
| US-20210032195-A1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | ELI LILLY AND COMPANY | 2021-02-04 | — | — | US | disclosed |
| US-20210002230-A1 | OXOACRIDINYL ACETIC ACID DERIVATIVES AND METHODS OF USE | Stingthera, Inc. | 2021-01-07 | — | — | US | disclosed |
| WO-2020232378-A1 | BENZO[B][1,8]NAPHTHYRIDINE ACETIC ACID DERIVATIVES AND METHODS OF USE | SILICON SWAT, INC. (US) | 2020-11-19 | — | — | WO | disclosed |
| US-10745358-B2 | Oxoacridinyl acetic acid derivatives and methods of use | SILICON SWAT, INC. (US) | 2020-08-18 | — | — | US | disclosed |
| US-10703712-B2 | Farnesoid X receptor agonists and uses thereof | METACRINE, INC. (US) | 2020-07-07 | — | — | US | disclosed |
| WO-2020116875-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | 두산솔루스 주식회사 | 2020-06-11 | — | — | WO | disclosed |
| US-10336747-B2 | Pyrimido[4,5-B]indole derivatives and use thereof in the expansion of hematopoietic stem cells | Université de Montréal | 2019-07-02 | — | — | US | disclosed |
| EP-0523845-A2 | New benzodiazepine analogs | MERCK & CO. INC. (US) | 1993-01-20 | — | — | EP | disclosed |
| WO-1992013552-A1 | ANTI-AGGREGATORY PEPTIDES CONTAINING AN AROMATIC ESTER OR AMIDE | SMITHKLINE BEECHAM CORPORATION (US) | 1992-08-20 | — | — | WO | disclosed |
| EP-0490590-A1 | New benzodiazepine analogs | MERCK & CO. INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0434369-A1 | New benzodiazepine analogs | MERCK & CO. INC. (US) | 1991-06-26 | — | — | EP | disclosed |
| EP-0434364-A2 | Benzodiazepine analogs for treating panic syndrome and for directly inducing analgesia | MERCK & CO. INC. (US) | 1991-06-26 | — | — | EP | disclosed |
| EP-0434360-A1 | New benziodiazepine analogs | MERCK & CO. INC. (US) | 1991-06-26 | — | — | EP | disclosed |
| EP-0038195-B1 | PHENYLAMINO SACCHARIDE DERIVATIVES, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-10-03 | — | — | EP | disclosed |
| US-4372948-A | Derivative of saccharide and physiologically active agent containing the same | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-02-08 | — | — | US | disclosed |
| EP-0038195-A1 | Phenylamino saccharide derivatives, their production and pharmaceutical compositions containing them | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1981-10-21 | — | — | EP | disclosed |
| US-4080322-A | WATER SOLUBLE DYES FOR LEATHER, PAPER, AND NON-WOVEN TEXTILES | SANDOZ LTD. (CH) | 1978-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203003-A1 | Notch Inhibitors and Uses Thereof | NOTCH1, NOTCH2, NOTCH4 | TDP1 2785/4885KMT2A 1979/4885SLC6A2 4868/4885 |
| US-20210032195-A1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | NR1H4, NR1H2, NR1H3 | TDP1 3839/4885KMT2A 4719/4885SLC6A2 4333/4885 |
| US-11214538-B2 | Farnesoid X receptor agonists and uses thereof | NR1H4, NR1H2, NR1H3 | TDP1 3839/4885KMT2A 4719/4885SLC6A2 4333/4885 |
| US-10703712-B2 | Farnesoid X receptor agonists and uses thereof | NR1H4, NR1H2, NR1H3 | TDP1 3839/4885KMT2A 4719/4885SLC6A2 4333/4885 |
| US-10336747-B2 | Pyrimido[4,5-B]indole derivatives and use thereof in the expansion of hematopoietic stem cells | IDO1, IDO2, INMT | TDP1 2505/4885KMT2A 772/4885SLC6A2 1309/4885 |
| US-20210002230-A1 | OXOACRIDINYL ACETIC ACID DERIVATIVES AND METHODS OF USE | STING1, IRF3, CGAS | TDP1 140/4885KMT2A 4787/4885SLC6A2 4585/4885 |
| US-10745358-B2 | Oxoacridinyl acetic acid derivatives and methods of use | STING1, IRF3, CGAS | TDP1 140/4885KMT2A 4787/4885SLC6A2 4585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.