Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20214949 | 0.94 | KMT2A (0.50) | NPC1RAB9ABCHECA1CA2 | |
| SCHEMBL27419910 | 0.88 | ALDH1A1 (0.53) | NPC1RAB9ACA1CA2SMN1; SMN2 | |
| SCHEMBL8000104 | 0.83 | BCHE (0.52) | RAB9ABCHEMAPTKMT2AALDH1A1 | |
| SCHEMBL15234456 | 0.81 | TSHR (0.61) | RAB9ABCHECA1SMN1; SMN2MAPT | |
| SCHEMBL22810886 | 0.77 | SMN1; SMN2 (0.54) | NPC1RAB9ASMN1; SMN2MAPTKMT2A | |
| SCHEMBL2542923 | 0.75 | CYP1A2 (0.47) | NPC1RAB9ACA1CA2MAPT | |
| SCHEMBL11176841 | 0.75 | THRB (0.48) | CA2SMN1; SMN2KMT2AALDH1A1CYP1A2 | |
| SCHEMBL6429495 | 0.75 | THRB (0.48) | CA2SMN1; SMN2KMT2AALDH1A1CYP1A2 | |
| SCHEMBL6737728 | 0.75 | HDAC6 (0.72) | RAB9ACA2MAPTPOLBLMNA | |
| SCHEMBL1009228 | 0.75 | KMT2A (0.76) | NPC1RAB9ASMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117996-A | COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS | NOVO NORDISK A/S (DK) | 2000-09-12 | — | — | US | disclosed |