Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Piperidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperidine SCHEMBL28040221 | 0.97 | ALDH1A1 (0.47) | ALDH1A1TSHRNAPRTTDP1CXCR4 | |
| Piperidine SCHEMBL27535943 | 0.97 | ALDH1A1 (0.47) | ALDH1A1TSHRNAPRTTDP1CXCR4 | |
| Piperidine SCHEMBL2420379 | 0.95 | ALDH1A1 (0.50) | ALDH1A1TSHRNAPRTTDP1CXCR4 | |
| Pyridine SCHEMBL812392 | 0.92 | TSHR (0.53) | ALDH1A1TSHRNAPRTTDP1CXCR4 | |
| Pyridine SCHEMBL28057559 | 0.90 | TSHR (0.50) | ALDH1A1TSHRNAPRTTDP1CXCR4 | |
| Pyridine SCHEMBL5210014 | 0.90 | CXCR4 (0.50) | ALDH1A1TSHRNAPRTTDP1CXCR4 | |
| Pyridine SCHEMBL8406615 | 0.90 | CXCR4 (0.50) | ALDH1A1TSHRNAPRTTDP1CXCR4 | |
| Piperazine SCHEMBL28224527 | 0.87 | TSHR (0.53) | ALDH1A1TSHRNAPRTTDP1CXCR4 | |
| Piperazine SCHEMBL1699696 | 0.87 | TSHR (0.60) | ALDH1A1TSHRNAPRTTDP1CXCR4 | |
| Pyridine SCHEMBL21497058 | 0.87 | TSHR (0.60) | ALDH1A1TSHRNAPRTTDP1CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979208-A4 | COMPOSITION AND METHOD FOR REDUCING COPPER OXIDE TO METALLIC COPPER | MORTON INT INC (US) | 2000-10-25 | — | — | EP | disclosed |
| EP-0979208-A1 | COMPOSITION AND METHOD FOR REDUCING COPPER OXIDE TO METALLIC COPPER | MORTON INTERNATIONAL, INC. (US) | 2000-02-16 | — | — | EP | disclosed |
| WO-1999042402-A1 | COMPOSITION AND METHOD FOR REDUCING COPPER OXIDE TO METALLIC COPPER | MORTON INTERNATIONAL, INC. (US) | 1999-08-26 | — | — | WO | disclosed |