Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | CHRNB2 | P17787 | 7/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL812392 | 0.94 | TSHR (0.53) | TSHRNAPRTTDP1CHRNB2CHRNA4 | |
| Pyridine SCHEMBL28057559 | 0.91 | TSHR (0.50) | TSHRNAPRTTDP1CHRNB2CHRNA4 | |
| Pyridine SCHEMBL5210014 | 0.91 | CXCR4 (0.50) | TSHRNAPRTTDP1CHRNB2CHRNA4 | |
| Pyridine SCHEMBL8406615 | 0.91 | CXCR4 (0.50) | TSHRNAPRTTDP1CHRNB2CHRNA4 | |
| Piperidine SCHEMBL2420379 | 0.91 | ALDH1A1 (0.50) | TSHRNAPRTTDP1CHRNB2CHRNA4 | |
| Pyridine SCHEMBL11825162 | 0.90 | — | — | |
| Piperidine SCHEMBL28040221 | 0.89 | ALDH1A1 (0.47) | TSHRNAPRTTDP1CHRNB2CHRNA4 | |
| Piperidine SCHEMBL27535943 | 0.89 | ALDH1A1 (0.47) | TSHRNAPRTTDP1CHRNB2CHRNA4 | |
| Piperazine SCHEMBL1699696 | 0.87 | TSHR (0.60) | TSHRNAPRTTDP1CHRNB2CHRNA4 | |
| Pyridine SCHEMBL29286575 | 0.87 | TSHR (0.60) | TSHRNAPRTTDP1CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230121082-A1 | COMPOSITIONS AND METHODS FOR PREPARING AND USING AZETIDINES | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2023-04-20 | — | — | US | disclosed |
| US-20210101884-A1 | COMPOSITIONS AND METHODS FOR PREPARING AND USING AZETIDINES | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2021-04-08 | — | — | US | disclosed |
| WO-2019204740-A1 | COMPOSITIONS AND METHODS FOR PREPARING AND USING AZETIDINES | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2019-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210101884-A1 | COMPOSITIONS AND METHODS FOR PREPARING AND USING AZETIDINES | DGKA, DGKK, PRKG2 | TSHR 2832/4885NAPRT 3940/4885TDP1 2471/4885 |
| US-20230121082-A1 | COMPOSITIONS AND METHODS FOR PREPARING AND USING AZETIDINES | DGKA, DGKK, PRKG2 | TSHR 2832/4885NAPRT 3940/4885TDP1 2471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.