Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL28057559 | 0.97 | TSHR (0.50) | TSHRNAPRTTDP1ALDH1A1CHRNB2 | |
| Piperidine SCHEMBL2420379 | 0.97 | ALDH1A1 (0.50) | TSHRNAPRTTDP1ALDH1A1CHRNB2 | |
| Piperidine SCHEMBL28040221 | 0.95 | ALDH1A1 (0.47) | TSHRNAPRTTDP1ALDH1A1CHRNB2 | |
| Piperidine SCHEMBL27535943 | 0.95 | ALDH1A1 (0.47) | TSHRNAPRTTDP1ALDH1A1CHRNB2 | |
| Pyridine SCHEMBL21497058 | 0.94 | TSHR (0.60) | TSHRNAPRTTDP1ALDH1A1CHRNB2 | |
| Piperidine SCHEMBL8000110 | 0.92 | ALDH1A1 (0.45) | TSHRNAPRTTDP1ALDH1A1CHRNB2 | |
| Pyridine SCHEMBL8406615 | 0.92 | CXCR4 (0.50) | TSHRNAPRTTDP1ALDH1A1CHRNB2 | |
| Pyridine SCHEMBL5210014 | 0.92 | CXCR4 (0.50) | TSHRNAPRTTDP1ALDH1A1CHRNB2 | |
| Pyridine SCHEMBL11825162 | 0.91 | — | — | |
| Pyridine SCHEMBL5878565 | 0.88 | TSHR (0.41) | TSHRNAPRTTDP1ALDH1A1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110563696-B | Process for preparing heteroatom-containing cyclohexene halide | 蚌埠产品质量监督检验研究院 | 2022-05-03 | — | — | CN | claimed |
| CN-107978733-B | Positive electrode for metal secondary battery, metal secondary battery including the same, and method of preparing the same | 三星电子株式会社 | 2022-02-18 | — | — | CN | claimed |
| CN-106058311-B | Electrolyte for lithium secondary battery and lithium secondary battery comprising the same | 三星电子株式会社 | 2021-11-12 | — | — | CN | claimed |
| CN-105390744-B | Composite, method of preparing the same, electrolyte comprising the same, and lithium secondary battery | 三星电子株式会社 | 2021-10-22 | — | — | CN | claimed |
| US-10221172-B2 | Benzothiazole and benzisothiazole-substituted compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction | VANDERBILT UNIVERSITY (US) | 2019-03-05 | — | — | US | claimed |
| US-20180022744-A1 | BENZOTHIAZOLE AND BENZISOTHIAZOLE-SUBSTITUTED COMPOUNDS AS MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION | VANDERBILT UNIVERSITY | 2018-01-25 | — | — | US | claimed |
| WO-2016115272-A1 | BENZOTHIAZOLE AND BENZISOTHIAZOLE-SUBSTITUTED COMPOUNDS AS MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION | VANDERBILT UNIVERSITY (US) | 2016-07-21 | — | — | WO | claimed |
| US-8415381-B2 | Heteroaryl compounds and their uses | NOVARTIS AG (CH) | 2013-04-09 | — | — | US | claimed |
| US-20110028492-A1 | Heteroaryl Compounds and Their Uses | NOVARTIS AG (CH) | 2011-02-03 | — | — | US | claimed |
| US-4629490-A | PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1986-12-16 | — | — | US | claimed |
| EP-0039310-B1 | PHOSPHONOMETHYLGLYCYLHYDROXAMIC ACID AND SALTS THEREOF, THEIR PREPARATION AND USE IN HERBICIDE COMPOSITIONS | CIBA-GEIGY AG (CH) | 1983-11-09 | — | — | EP | claimed |
| US-4414158-A | Phosphonomethylglycylhydroxamic acid and novel herbicidally active salts thereof | CIBA-GEIGY CORPORATION (US) | 1983-11-08 | — | — | US | claimed |
| US-20230212533-A1 | PRODUCTS AND METHODS FOR THE TREATMENT OF NICOTINE DEPENDENCE | THE BOARD OF TRUSTEES OF WESTERN MICHIGAN UNIVERSITY | 2023-07-06 | — | — | US | disclosed |
| CN-116034157-A | Products and methods for treating nicotine dependence | 密歇根大学董事会 | 2023-04-28 | — | — | CN | disclosed |
| EP-4158006-A2 | PRODUCTS AND METHODS FOR THE TREATMENT OF NICOTINE DEPENDENCE | The Regents of The University of Michigan (US) | 2023-04-05 | — | — | EP | disclosed |
| US-11532852-B2 | Composite membrane, and lithium battery including the composite membrane | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2022-12-20 | — | — | US | disclosed |
| WO-2001029245-A2 | ENZYMATIC PROCESS FOR THE RESOLUTION OF ENANTIOMERIC MIXTURES OF β-LACTAMS | FLORIDA STATE UNIVERSITY (US) | 2001-04-26 | — | — | WO | disclosed |
| US-4629490-A | PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1986-12-16 | — | — | US | disclosed |
| US-4414158-A | Phosphonomethylglycylhydroxamic acid and novel herbicidally active salts thereof | CIBA-GEIGY CORPORATION (US) | 1983-11-08 | — | — | US | disclosed |
| US-4093620-A | Process for producing 2-cyano N-substituted heterocyclic compounds and products produced thereby | PHILIP MORRIS INCORPORATED (US) | 1978-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022744-A1 | BENZOTHIAZOLE AND BENZISOTHIAZOLE-SUBSTITUTED COMPOUNDS AS MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION | GRM4, GRIK4, GRIA4 | TSHR 604/4885NAPRT 2460/4885TDP1 1490/4885 |
| US-10221172-B2 | Benzothiazole and benzisothiazole-substituted compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction | GRM4, GRIK4, GRIA4 | TSHR 604/4885NAPRT 2460/4885TDP1 1490/4885 |
| US-20110028492-A1 | Heteroaryl Compounds and Their Uses | CDK9, CDK19, CDK3 | TSHR 2674/4885NAPRT 2237/4885TDP1 1407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.