Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8342155 | 0.85 | GAA (0.37) | HPGDGAARAPGEF4MAPTCYP1A2 | |
| SCHEMBL13060991 | 0.79 | HPGD (0.37) | HPGDGAARAPGEF4MAPTCYP1A2 | |
| SCHEMBL9706128 | 0.79 | HPGD (0.41) | HPGDGAARAPGEF4MAPTCYP1A2 | |
| SCHEMBL19848397 | 0.79 | CYP1A2 (0.39) | HPGDGAARAPGEF4MAPTCYP1A2 | |
| SCHEMBL24569887 | 0.78 | SIGMAR1 (0.37) | GAAMAPTKDM4EHTTLMNA | |
| SCHEMBL12889181 | 0.77 | HPGD (0.45) | HPGDGAARAPGEF4CYP1A2KDM4E | |
| SCHEMBL1485811 | 0.73 | TDP1 (0.42) | HPGDGAARAPGEF4MAPTCYP1A2 | |
| SCHEMBL12740474 | 0.71 | POLB (0.43) | HPGDGAAMAPTKDM4ELMNA | |
| SCHEMBL16502159 | 0.71 | MAPT (0.42) | GAAMAPTCYP1A2KDM4EHTT | |
| SCHEMBL2092832 | 0.70 | RAPGEF4 (0.56) | GAARAPGEF4KDM4EHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119088-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |