Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.67 |
| ▸ | CA1 | P00915 | 14/20 | 0.67 |
| ▸ | CA12 | O43570 | 8/20 | 0.67 |
| ▸ | CA9 | Q16790 | 8/20 | 0.67 |
| ▸ | CA4 | P22748 | 5/20 | 0.57 |
| ▸ | CA6 | P23280 | 5/20 | 0.57 |
| ▸ | CA5A | P35218 | 5/20 | 0.57 |
| ▸ | CA7 | P43166 | 5/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.57 |
| ▸ | MIF | P14174 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1737052 | 0.81 | GRIN1 (0.62) | — | |
| SCHEMBL3665119 | 0.78 | MIF (0.61) | CA2CA1CA12CA9CA4 | |
| Sulfuric Acid SCHEMBL10891220 | 0.77 | LMNA (0.54) | CA2CA1CA12CA9 | |
| SCHEMBL13667799 | 0.76 | MIF (0.65) | CA2CA1CA12CA9CA4 | |
| Sulfuric Acid SCHEMBL11883316 | 0.75 | F2 (0.46) | CA2CA1CA12CA9 | |
| Sulfuric Acid SCHEMBL4014387 | 0.74 | LMNA (0.65) | — | |
| Sulfuric Acid SCHEMBL10890618 | 0.74 | F2 (0.53) | CA2CA1CA12CA9CA4 | |
| SCHEMBL4094076 | 0.73 | GRIN2D (0.54) | CA2CA1CA12CA9 | |
| SCHEMBL7635935 | 0.73 | GRIN1 (0.54) | — | |
| SCHEMBL1009797 | 0.73 | CA2 (1.00) | CA2CA1CA12CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000009115-A1 | GRP RECEPTOR LIGANDS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-24 | — | — | WO | disclosed |