Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.50 |
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.50 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.50 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.50 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.50 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.57 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.57 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.57 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.57 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.57 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.57 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.57 |
| ▸ | HTR3A | P46098 | 2/20 | 0.56 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.56 |
| ▸ | HTR3B | O95264 | 1/20 | 0.56 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45769 | 0.89 | GRIN2B (0.68) | LMNAPMP22SMN1; SMN2GRIN2BGRIN1 | |
| Hydrochloric Acid SCHEMBL4629266 | 0.87 | GRIN2B (0.72) | LMNASMN1; SMN2GRIN2BGRIN1GRIN2D | |
| SCHEMBL7206541 | 0.87 | GRIN2B (0.65) | LMNAPMP22SMN1; SMN2GRIN2BGRIN1 | |
| Sulfuric Acid SCHEMBL10891220 | 0.82 | LMNA (0.54) | LMNAPMP22SMN1; SMN2GRIN2BGRIN1 | |
| [11C]Phenethylguanidine SCHEMBL11556997 | 0.81 | HTR3A (0.67) | LMNAPMP22SMN1; SMN2GRIN2BGRIN1 | |
| Sulfuric Acid SCHEMBL11555700 | 0.80 | GRIN2B (0.56) | LMNAPMP22SMN1; SMN2GRIN2BGRIN1 | |
| Sulfuric Acid SCHEMBL11555704 | 0.80 | GRIN2B (0.56) | LMNAPMP22SMN1; SMN2GRIN2BGRIN1 | |
| Sulfuric Acid SCHEMBL28338880 | 0.80 | NOS2 (0.51) | LMNAPMP22SMN1; SMN2GRIN2BGRIN1 | |
| Iobenguane SCHEMBL29435410 | 0.79 | SMN1; SMN2 (1.00) | LMNAPMP22SMN1; SMN2GRIN2BGRIN1 | |
| Iobenguane SCHEMBL29722658 | 0.79 | SMN1; SMN2 (1.00) | LMNAPMP22SMN1; SMN2GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115884734-A | Medical implant for marking a surgical site | 特法公司 | 2023-03-31 | — | — | CN | disclosed |
| WO-2009087395-A1 | WEIGHT REDUCING COMPOUNDS | UNIVERSITY OF STRATHCLYDE (GB) | 2009-07-16 | — | — | WO | disclosed |
| US-4279899-A | MICROBIOCIDES | BASF AKTIENGESELLSCHAFT (DE) | 1981-07-21 | — | — | US | disclosed |
| US-4147804-A | ANTIARRHYTHMIA AGENTS | WILLIAM H. RORER, INC. (US) | 1979-04-03 | — | — | US | disclosed |