Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA5 | P30532 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7627296 | 0.81 | MAPT (0.36) | GAAMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL7996172 | 0.75 | CYP11B1 (0.34) | F2HSD17B10CHRNB2CHRNA5CHRNA4 | |
| SCHEMBL7634848 | 0.75 | MAPT (0.38) | F2KMT2AALDH1A1HSD17B10CHRNB2 | |
| SCHEMBL7638011 | 0.71 | MAPT (0.45) | GAAMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL8002213 | 0.67 | CYP11B1 (0.37) | F2HTTALDH1A1HSD17B10MAPK1 | |
| SCHEMBL7243590 | 0.66 | PTGS2 (0.39) | GAAMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL7243090 | 0.66 | EPHX2 (0.42) | GAAMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL7244506 | 0.58 | PTGS2 (0.42) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL7243350 | 0.58 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL9901553 | 0.57 | ALDH1A1 (0.50) | GAAMEN1KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001072740-A1 | SUBSTITUTED 1-(4-AMINOPHENYL) TRIAZOLES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2001-10-04 | — | — | WO | claimed |