Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA5 | P30532 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7634848 | 0.94 | MAPT (0.38) | MAPTALDH1A1KDM4ETHRBHDAC1 | |
| SCHEMBL7638011 | 0.90 | MAPT (0.45) | MAPTALDH1A1KDM4EPLA2G1BGAA | |
| SCHEMBL7243590 | 0.83 | PTGS2 (0.39) | MAPTALDH1A1KDM4EPLA2G1BGAA | |
| SCHEMBL7243090 | 0.83 | EPHX2 (0.42) | MAPTALDH1A1KDM4EPLA2G1BGAA | |
| SCHEMBL8002230 | 0.81 | GAA (0.35) | MAPTALDH1A1KDM4EGAAHTT | |
| SCHEMBL7634838 | 0.76 | MAPT (0.46) | MAPTALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL7243350 | 0.76 | ALDH1A1 (0.46) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL7244506 | 0.76 | PTGS2 (0.42) | ALDH1A1KDM4EHDAC1HDAC6ABL1 | |
| SCHEMBL7630672 | 0.75 | HDAC1 (0.42) | MAPTTHRBHDAC1HDAC6 | |
| SCHEMBL7635227 | 0.74 | CHRNB2 (0.39) | CHRNB2CHRNA5CHRNA4KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451820-B1 | Substituted 1-(4-aminophenly)triazoles and their use as anti-inflammatory agents | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-09-17 | — | — | US | claimed |
| WO-2001072740-A1 | SUBSTITUTED 1-(4-AMINOPHENYL) TRIAZOLES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2001-10-04 | — | — | WO | claimed |