Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.60 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998940 | 0.95 | NFE2L2 (0.64) | NFE2L2RELAFBP1TUBB4ATUBB | |
| SCHEMBL7998331 | 0.87 | NFE2L2 (0.48) | NFE2L2RELAFBP1 | |
| SCHEMBL7998337 | 0.86 | NFE2L2 (0.62) | NFE2L2RELAFBP1XDHEGFR | |
| SCHEMBL8001633 | 0.84 | NFE2L2 (0.50) | NFE2L2RELAFBP1 | |
| SCHEMBL7998334 | 0.83 | PTGES2 (0.46) | NFE2L2FBP1 | |
| SCHEMBL8001632 | 0.83 | MAPT (0.48) | NFE2L2FBP1EGFR | |
| SCHEMBL8002658 | 0.82 | NFE2L2 (0.45) | NFE2L2RELAFBP1TUBB4ATUBB | |
| SCHEMBL7990203 | 0.80 | NFE2L2 (0.47) | NFE2L2FBP1 | |
| SCHEMBL8002639 | 0.78 | NFE2L2 (0.43) | NFE2L2FBP1 | |
| SCHEMBL7990162 | 0.78 | ALDH1A1 (0.51) | NFE2L2FBP1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120783-A1 | HIGH AFFINITY INHIBITORS OF HEPATITIS C VIRUS NS3/4A PROTEASE | THE JOHNS HOPKINS UNIVERSITY (US) | 2009-10-01 | — | — | WO | disclosed |