Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL906472 | 0.86 | KMT2A (0.47) | KMT2AMEN1NSD2GAAPLCG1 | |
| SCHEMBL3531002 | 0.82 | VCAM1 (0.44) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL6971370 | 0.78 | KMT2A (0.68) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL57882 | 0.74 | TSHR (0.40) | KMT2AMEN1CASP6TDP1ALDH1A1 | |
| SCHEMBL5663517 | 0.74 | TTR (0.32) | ALDH1A1NT5ETSHRSMN1; SMN2 | |
| SCHEMBL151052 | 0.73 | KMT2A (0.70) | KMT2AMEN1GAACA1CA2 | |
| SCHEMBL1028675 | 0.73 | GPR35 (0.47) | KMT2AMEN1L3MBTL1CA1CA2 | |
| SCHEMBL9754556 | 0.73 | KMT2A (0.70) | KMT2AMEN1GAACA1CA2 | |
| SCHEMBL63933 | 0.73 | KMT2A (0.70) | KMT2AMEN1GAACA1CA2 | |
| SCHEMBL588012 | 0.73 | TTR (0.41) | KMT2AMEN1NSD2GAACASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594047-B1 | Arylazo chromoionophores | BAYER AG (US) | 2000-01-05 | — | — | EP | claimed |
| US-5310888-A | Calcium detection | MILES INC. (US) | 1994-05-10 | — | — | US | claimed |
| EP-0594047-A1 | Arylazo chromoionophores | Bayer Corporation (US) | 1994-04-27 | — | — | EP | claimed |
| EP-0594047-B1 | Arylazo chromoionophores | BAYER AG (US) | 2000-01-05 | — | — | EP | disclosed |
| US-5310888-A | Calcium detection | MILES INC. (US) | 1994-05-10 | — | — | US | disclosed |
| EP-0594047-A1 | Arylazo chromoionophores | Bayer Corporation (US) | 1994-04-27 | — | — | EP | disclosed |