Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2041279 | 0.81 | KMT2A (1.00) | KMT2AKIF18AMEN1RAB9AHTR6 | |
| SCHEMBL8002521 | 0.78 | KMT2A (0.43) | KMT2AKIF18AMEN1POLBALDH1A1 | |
| SCHEMBL3531002 | 0.78 | VCAM1 (0.44) | KMT2AKIF18AMEN1POLBALDH1A1 | |
| SCHEMBL4783767 | 0.78 | HTR6 (0.61) | KMT2AHTR6GFERNPSR1POLB | |
| SCHEMBL8208093 | 0.78 | KMT2A (0.93) | KMT2AKIF18AMEN1RAB9AHTR6 | |
| SCHEMBL10040107 | 0.76 | KIF18A (0.68) | KMT2AKIF18AMEN1RAB9AHTR6 | |
| SCHEMBL5454671 | 0.76 | HTR6 (0.46) | KMT2AKIF18AHTR6GFERNPSR1 | |
| SCHEMBL28252471 | 0.75 | HTR6 (0.45) | KMT2AKIF18AMEN1HTR6MAPT | |
| SCHEMBL22028032 | 0.75 | POLB (0.50) | KMT2AKIF18AMEN1HTR6GFER | |
| SCHEMBL11590219 | 0.74 | KMT2A (0.63) | KMT2AKIF18AMEN1RAB9AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1433407-A | Bis-aryl sulfones | PHARMACIA & UP JOHN CO (US) | 2003-07-30 | — | — | CN | disclosed |
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |