Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL8013938 | 0.98 | LMNA (0.47) | LMNAMEN1MAPTALOX12KMT2A | |
| SCHEMBL8021733 | 0.90 | MEN1 (0.47) | LMNAMEN1MAPTALOX12KMT2A | |
| SCHEMBL5954165 | 0.89 | MEN1 (0.50) | LMNAMEN1MAPTALOX12KMT2A | |
| SCHEMBL909810 | 0.89 | CA2 (0.51) | LMNAMEN1MAPTALOX12KMT2A | |
| SCHEMBL909808 | 0.89 | CA2 (0.51) | LMNAMEN1MAPTALOX12KMT2A | |
| SCHEMBL3821974 | 0.89 | MEN1 (0.50) | LMNAMEN1MAPTALOX12KMT2A | |
| SCHEMBL4728709 | 0.85 | MEN1 (0.47) | LMNAMEN1MAPTALOX12KMT2A | |
| SCHEMBL7162403 | 0.82 | MGLL (0.51) | LMNAMEN1MAPTALOX12KMT2A | |
| SCHEMBL7162407 | 0.82 | MGLL (0.51) | LMNAMEN1MAPTALOX12KMT2A | |
| SCHEMBL28209015 | 0.81 | PPARG (0.52) | LMNAMEN1MAPTALOX12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000041685-A1 | CCR-3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-07-20 | — | — | WO | disclosed |