Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909808 | 1.00 | CA2 (0.51) | CA2PPARGMEN1LMNAMAPT | |
| SCHEMBL3821974 | 0.91 | MEN1 (0.50) | MEN1LMNAMAPTALOX12KMT2A | |
| SCHEMBL5954165 | 0.91 | MEN1 (0.50) | MEN1LMNAMAPTALOX12KMT2A | |
| SCHEMBL8002622 | 0.89 | LMNA (0.48) | MEN1LMNAMAPTALOX12KMT2A | |
| SCHEMBL5026174 | 0.88 | CA2 (0.55) | CA2PPARGMEN1LMNAKMT2A | |
| SCHEMBL8021733 | 0.88 | MEN1 (0.47) | PPARGMEN1LMNAMAPTALOX12 | |
| Hydrochloric Acid SCHEMBL27675903 | 0.87 | CA2 (0.54) | CA2PPARGMEN1LMNAKMT2A | |
| Hydrochloric Acid SCHEMBL28059744 | 0.87 | CA2 (0.54) | CA2PPARGMEN1LMNAKMT2A | |
| SCHEMBL4728709 | 0.87 | MEN1 (0.47) | PPARGMEN1LMNAMAPTALOX12 | |
| Iodide SCHEMBL8013938 | 0.87 | LMNA (0.47) | MEN1LMNAMAPTALOX12KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0843672-B1 | ONE POT SYNTHESIS OF 2-OXAZOLIDINONE DERIVATIVES | ASTRAZENECA AB (SE) | 2002-11-13 | — | — | EP | claimed |
| EP-0843673-B1 | ONE POT SYNTHESIS OF 2-OXAZOLIDINONE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-11-07 | — | — | EP | claimed |
| US-8426588-B2 | Phenylalanine derivatives | AJINOMOTO CO, INC. (JP) | 2013-04-23 | — | — | US | disclosed |
| US-20120253041-A1 | NEW PHENYLALANINE DERIVATIVES | AJINOMOTO CO., INC. (JP) | 2012-10-04 | — | — | US | disclosed |
| US-8222405-B2 | Phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2012-07-17 | — | — | US | disclosed |
| US-20110065918-A1 | NEW PHENYLALANINE DERIVATIVES | AJINOMOTO CO., INC. (JP) | 2011-03-17 | — | — | US | disclosed |
| EP-1288205-B1 | NOVEL PHENYLALANINE DERIVATIVES | AJINOMOTO KK (JP) | 2011-02-02 | — | — | EP | disclosed |
| US-7872125-B2 | Phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2011-01-18 | — | — | US | disclosed |
| EP-1477482-B1 | NOVEL PHENYLALANINE DERIVATIVE | AJINOMOTO KK (JP) | 2010-04-14 | — | — | EP | disclosed |
| US-7605165-B2 | Phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2009-10-20 | — | — | US | disclosed |
| US-7153963-B2 | Phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2006-12-26 | — | — | US | disclosed |
| EP-0843673-B1 | ONE POT SYNTHESIS OF 2-OXAZOLIDINONE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-11-07 | — | — | EP | disclosed |
| US-6303791-B1 | REACTING METHYL 4-NITRO-(L)-PHENYLALANINATE HYDROCHLORIDE WITH N-BUTYL CHLOROFORMATE TO FORM CARBAMATE, REDUCING NITRO GROUP TO AMINE AND ESTER GROUP TO ALCOHOL, CYCLIZING, FORMING DIAZONIUM SALT, REDUCING, PERFORMING FISCHER REACTION | ZENECA LIMITED (GB) | 2001-10-16 | — | — | US | disclosed |
| US-6160123-A | One pot synthesis of 2-oxazolidinone derivatives | ZENECA, LTD. (GB) | 2000-12-12 | — | — | US | disclosed |
| WO-2000051976-A1 | REGIOSELECTIVE SYNTHESIS OF DTPA DERIVATIVES | IDEC PHARMACEUTICALS CORPORATION (US) | 2000-09-08 | — | — | WO | disclosed |
| US-6084103-A | FORMING A CARBAMATE FROM METHYL 4-NITRO-(L)-PHENYLALANINATE HYDROCHLORIDE; REDUCING THE NITRO AND ESTER GROUPS; RING CLOSURE FREE OF PHOSGENE; FORMING A DIAZONIUM SALT WITHOUT USING TIN CHLORIDE; FISCHER REACTION; MIGRAINES; 5HT1-AGONIST | ZENECA LIMITED (GB) | 2000-07-04 | — | — | US | disclosed |
| EP-0843673-A1 | ONE POT SYNTHESIS OF 2-OXAZOLIDINONE DERIVATIVES | ZENECA LIMITED (GB) | 1998-05-27 | — | — | EP | disclosed |
| EP-0843672-A1 | ONE POT SYNTHESIS OF 2-OXAZOLIDINONE DERIVATIVES | ZENECA LIMITED (GB) | 1998-05-27 | — | — | EP | disclosed |
| WO-1997006163-A1 | ONE POT SYNTHESIS OF 2-OXAZOLIDINONE DERIVATIVES | ZENECA LIMITED (GB) | 1997-02-20 | — | — | WO | disclosed |
| WO-1997006162-A1 | ONE POT SYNTHESIS OF 2-OXAZOLIDINONE DERIVATIVES | ZENECA LIMITED (GB) | 1997-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065918-A1 | NEW PHENYLALANINE DERIVATIVES | ITGB4, ITGA4, ITGAV | CA2 4829/4885PPARG 2935/4885MEN1 4326/4885 |
| US-20120253041-A1 | NEW PHENYLALANINE DERIVATIVES | ITGB4, ITGA4, ITGAV | CA2 4829/4885PPARG 2935/4885MEN1 4326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.