Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 4/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.51 |
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.47 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985219 | 0.87 | LMNA (0.54) | PTGESALOX5PPARGMMP9PPARA | |
| SCHEMBL7999764 | 0.87 | LDHA (0.50) | ALOX5MMP1MMP3ALDH1A1KMT2A | |
| SCHEMBL8041180 | 0.81 | PPARG (0.61) | PTGESALOX5PPARGMMP3PPARA | |
| SCHEMBL27028936 | 0.77 | S1PR2 (0.54) | LMNAL3MBTL1MEN1USP2ALDH1A1 | |
| SCHEMBL27132568 | 0.77 | S1PR2 (0.54) | LMNAL3MBTL1MEN1USP2ALDH1A1 | |
| SCHEMBL27301137 | 0.76 | LTA4H (0.56) | LMNAL3MBTL1S1PR4S1PR1S1PR3 | |
| SCHEMBL28588860 | 0.75 | LMNA (0.68) | LMNAL3MBTL1MEN1USP2ALDH1A1 | |
| SCHEMBL28380845 | 0.75 | LMNA (0.68) | LMNAL3MBTL1MEN1USP2ALDH1A1 | |
| SCHEMBL4301825 | 0.75 | CA2 (0.57) | MAPK1FFAR1 | |
| SCHEMBL7995811 | 0.75 | LMNA (0.71) | LMNAL3MBTL1MEN1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009113320-A1 | MMP INHIBITOR | 株式会社ヤクルト本社 (JP) | 2009-09-17 | — | — | WO | disclosed |