SCHEMBL9250756

SCHEMBL9250756

O=C(c1ccc(Cl)cc1)c1cc(-c2ccccc2)c(O)c(-c2ccccc2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 4/20 0.53
CNR2 P34972 3/20 0.53
SRD5A2 P31213 2/20 0.52
MAPK1 P28482 1/20 0.52
MAPT P10636 2/20 0.49
POLB P06746 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
NR4A1 P22736 1/20 0.49
MMP2 P08253 1/20 0.47
MMP3 P08254 1/20 0.47
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
RAB9A P51151 2/20 0.46
NPC1 O15118 1/20 0.46
ALDH1A1 P00352 1/20 0.46
CYP1A2 P05177 1/20 0.46
SERPINE1 P05121 1/20 0.44
MEN1 O00255 1/20 0.44
LMNA P02545 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8003100 0.88 ALDH1A1 (0.56) CNR1CNR2SRD5A2MAPTMMP2
SCHEMBL10726242 0.83 CNR2 (0.50) CNR1CNR2MAPK1MAPTPOLB
SCHEMBL10874927 0.80 SRD5A2 (0.65) CNR1SRD5A2MAPK1MAPTPOLB
SCHEMBL50462 0.78 SRD5A2 (0.74) SRD5A2MAPK1MAPTNR4A1CES2
SCHEMBL9442387 0.78 SRD5A2 (0.74) SRD5A2MAPK1MAPTNR4A1CES2
SCHEMBL26803787 0.77 NR4A1 (0.53) CNR1SRD5A2MAPK1MAPTPOLB
SCHEMBL10953514 0.76 RAB9A (0.67) CNR1CNR2SRD5A2MAPK1MAPT
SCHEMBL29279320 0.76 PTPN1 (0.58) MAPK1MAPTALDH1A1LMNAPTPN1
SCHEMBL7465267 0.76 NR4A1 (0.66) SRD5A2MAPTPOLBNPSR1NR4A1
Hydrochloric Acid SCHEMBL4594201 0.76 SRD5A2 (0.71) SRD5A2MAPK1MAPTNR4A1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5395914-A Nucleophilic polycondensation of hydroxy halogen xanthones HOECHST AKTIENGESELLSCHAFT (DE) 1995-03-07 US disclosed
EP-0571883-A1 Polyarylethers with xanthone units, method for their production and their application HOECHST AKTIENGESELLSCHAFT (DE) 1993-12-01 EP disclosed