Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TACR2 | P21452 | 3/20 | 0.31 |
| ▸ | TACR3 | P29371 | 3/20 | 0.31 |
| ▸ | TACR1 | P25103 | 2/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8006166 | 0.87 | RORC (0.31) | — | |
| SCHEMBL15216114 | 0.81 | GAA (0.38) | MEN1KMT2A | |
| SCHEMBL12708305 | 0.79 | TYR (0.48) | MEN1KMT2A | |
| SCHEMBL3797063 | 0.75 | GAA (0.37) | MEN1KMT2A | |
| SCHEMBL7996164 | 0.69 | RAB9A (0.37) | MEN1KMT2A | |
| SCHEMBL12708298 | 0.69 | TYR (0.47) | MEN1KMT2A | |
| SCHEMBL12708307 | 0.68 | TYR (0.48) | MEN1KMT2A | |
| SCHEMBL15216089 | 0.67 | ALDH1A1 (0.38) | MEN1KMT2A | |
| SCHEMBL12708302 | 0.67 | TYR (0.47) | MEN1KMT2A | |
| SCHEMBL10118822 | 0.67 | DHODH (0.38) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009099596-A2 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX PHARAMACEUTICALS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |