Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8003571 | 0.87 | MEN1 (0.31) | — | |
| SCHEMBL3797063 | 0.81 | GAA (0.37) | RORC | |
| SCHEMBL12708302 | 0.77 | TYR (0.47) | — | |
| SCHEMBL6844911 | 0.77 | ADORA2A (0.35) | — | |
| SCHEMBL6844939 | 0.74 | LGALS1 (0.30) | — | |
| SCHEMBL15216114 | 0.74 | GAA (0.38) | — | |
| SCHEMBL12708308 | 0.73 | PPARA (0.40) | — | |
| SCHEMBL6844915 | 0.72 | — | — | |
| SCHEMBL6844928 | 0.72 | — | — | |
| SCHEMBL8005665 | 0.69 | RORC (0.37) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009099596-A2 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX PHARAMACEUTICALS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |