Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8000762 | 0.88 | MME (0.39) | RAB9AALDH1A1CYP3A4SMN1; SMN2NPC1 | |
| SCHEMBL8004256 | 0.82 | HDAC3 (0.47) | PKML3MBTL1NOTUMSMN1; SMN2LMNA | |
| SCHEMBL24767438 | 0.70 | HSD17B10 (0.59) | RAB9AHTTPKMALOX15FFAR2 | |
| SCHEMBL2435089 | 0.67 | RAB9A (0.60) | RAB9AHTTPKMALOX15FFAR2 | |
| SCHEMBL21210988 | 0.66 | LMNA (0.64) | RAB9AHTTALOX15NPC1LMNA | |
| SCHEMBL12952768 | 0.65 | HDAC3 (0.46) | ALDH1A1LMNANPSR1KMT2A | |
| Benzene SCHEMBL7286102 | 0.65 | HTT (0.59) | RAB9AHTTPKML3MBTL1ALDH1A1 | |
| SCHEMBL18439983 | 0.64 | RAB9A (0.61) | RAB9AHTTPKMALOX15FFAR2 | |
| SCHEMBL1911526 | 0.64 | HTT (0.67) | RAB9AHTTPKMALDH1A1ALOX15 | |
| SCHEMBL14032665 | 0.64 | RAB9A (0.64) | RAB9AHTTPKMALOX15FFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119088-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |