Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004014 | 0.88 | RAB9A (0.41) | KMT2ANPC1RAB9AALDH1A1LMNA | |
| SCHEMBL8006929 | 0.88 | KLK7 (0.40) | KLK7MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7992235 | 0.78 | LMNA (0.46) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL8001897 | 0.69 | HDAC1 (0.48) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL8004256 | 0.69 | HDAC3 (0.47) | MEN1KMT2ALMNASMN1; SMN2POLB | |
| SCHEMBL12952768 | 0.67 | HDAC3 (0.46) | HSD17B10MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9709062 | 0.66 | MME (0.56) | MMEACEHSD17B10KLK7MEN1 | |
| SCHEMBL31290862 | 0.66 | MME (0.59) | MMEACETSHRHSD17B10MEN1 | |
| SCHEMBL10067641 | 0.66 | MME (0.59) | MMEACETSHRHSD17B10MEN1 | |
| SCHEMBL1491201 | 0.66 | HSD17B10 (0.69) | MMEACETSHRHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119088-A1 | HETEROCYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2009-10-01 | — | — | WO | disclosed |