SCHEMBL8004640

SCHEMBL8004640

CCCCCCCCC=CCCCCCCCC(=O)OCCC(NC(=O)CCCN1CCCC1)OC(=O)CCCCCCCC=CCCCCCCCC

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 2/20 0.44
PRKCE Q02156 1/20 0.44
PRKCQ Q04759 1/20 0.44
PRKCD Q05655 1/20 0.44
DEGS1 O15121 1/20 0.43
ALDH1A1 P00352 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
DGKA P23743 1/20 0.41
CETP P11597 1/20 0.41
EPHX2 P34913 1/20 0.40
SLC6A5 Q9Y345 1/20 0.40
LPAR3 Q9UBY5 1/20 0.40
MGLL Q99685 1/20 0.40
NOD1 Q9Y239 1/20 0.40
THRB P10828 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8004467 0.82 DNM1 (0.50) PRKCAPRKCEPRKCQPRKCDDEGS1
SCHEMBL8016949 0.81 PRKCA (0.47) PRKCAPRKCEPRKCQPRKCDDEGS1
SCHEMBL8004637 0.80 DEGS1 (0.40) DEGS1ALDH1A1SLC6A5LPAR3THRB
SCHEMBL8004646 0.80 DEGS1 (0.40) DEGS1ALDH1A1SLC6A5LPAR3THRB
SCHEMBL2835881 0.80 MGLL (0.51) ALDH1A1DGKAEPHX2MGLLTHRB
SCHEMBL8020701 0.80 PRKCA (0.47) PRKCAPRKCEPRKCQPRKCDDEGS1
SCHEMBL8013363 0.79 PRKCA (0.67) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL8012919 0.79 PRKCA (0.67) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL8013367 0.79 PRKCA (0.67) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL8012917 0.79 PRKCA (0.67) PRKCAPRKCEPRKCQPRKCDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0685234-B1 DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER NIPPON SHINYAKU CO LTD (JP) 2000-05-10 EP disclosed
US-6020317-A Glycerol derivative, device and pharmaceutical composition NIPPON SHINYAKU CO. LTD. (JP) 2000-02-01 US disclosed
US-5705188-A LIPID MIXTURE, ANTITUMOR AGENTS NIPPON SHINYAKU COMPANY, LTD. (JP) 1998-01-06 US disclosed
EP-0685457-A1 GLYCEROL DERIVATIVE, DEVICE AND PHARMACEUTICAL COMPOSITION NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-12-06 EP disclosed
EP-0685234-A1 DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-12-06 EP disclosed