Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | ALPL | P05186 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.41 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8831746 | 0.84 | PLK1 (0.47) | ALOX15HTTNPC1RAB9AALDH1A1 | |
| SCHEMBL8880848 | 0.84 | PDE4B (0.43) | ALOX15HTTALPLNPC1RAB9A | |
| SCHEMBL8181320 | 0.81 | HTT (0.49) | ALOX15HTTALPLALDH1A1GAA | |
| SCHEMBL8172598 | 0.79 | VCAM1 (0.43) | ALOX15HTTALPLALDH1A1SMN1; SMN2 | |
| SCHEMBL8186182 | 0.79 | ALPL (0.57) | ALPLALDH1A1GAA | |
| SCHEMBL8186035 | 0.79 | KMT2A (0.47) | ALPLALDH1A1 | |
| SCHEMBL265015 | 0.79 | ALOX15 (1.00) | ALOX15HTTNPC1RAB9AALDH1A1 | |
| SCHEMBL30718649 | 0.79 | ALOX15 (1.00) | ALOX15HTTNPC1RAB9AALDH1A1 | |
| SCHEMBL8182321 | 0.78 | ALPL (0.45) | ALOX15HTTALPLNPC1RAB9A | |
| SCHEMBL27928930 | 0.77 | ALOX15 (0.97) | ALOX15HTTNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022899-A | EFFECTIVE INHIBITORS OF THE CELLULAR SODIUM PROTON ANTIPORTER | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-02-08 | — | — | US | disclosed |
| US-5753710-A | INHIBITORS OF THE CELLULAR SODIUM PROTON ANTIPORTER | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-05-19 | — | — | US | disclosed |