Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | ACHE | P22303 | 4/20 | 0.60 |
| ▸ | BCHE | P06276 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.59 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | GFER | P55789 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7941639 | 0.97 | ACHE (0.61) | KMT2AMEN1ACHEBCHEMAPT | |
| Hydrochloric Acid SCHEMBL7946348 | 0.96 | KMT2A (0.62) | KMT2AMEN1ACHEBCHEPOLB | |
| SCHEMBL7944955 | 0.96 | BCHE (0.61) | KMT2AMEN1ACHEBCHEMAPT | |
| SCHEMBL7944948 | 0.81 | KMT2A (0.64) | KMT2AMEN1ACHEBCHEKDM4E | |
| SCHEMBL16684277 | 0.80 | ACHE (0.66) | KMT2AACHEBCHE | |
| SCHEMBL7935344 | 0.80 | KMT2A (0.68) | KMT2AMEN1ACHEBCHEPOLB | |
| SCHEMBL29522722 | 0.80 | ACHE (0.66) | KMT2AACHEBCHE | |
| SCHEMBL7935378 | 0.80 | ACHE (0.60) | ACHEBCHE | |
| SCHEMBL5470535 | 0.79 | KMT2A (1.00) | KMT2AMEN1ACHEBCHENPC1 | |
| SCHEMBL7935359 | 0.78 | BCHE (0.61) | KMT2AMEN1ACHEBCHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6075144-A | ABILITY TO INHIBIT ACETYLCHOLINESTERASE; TREATS ALZHEIMER,S DISEASE | HOECHST MARION ROUSSEL, INC. (US) | 2000-06-13 | — | — | US | claimed |