Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 9/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.77 |
| ▸ | GFER | P55789 | 3/20 | 0.77 |
| ▸ | NPC1 | O15118 | 2/20 | 0.77 |
| ▸ | ATM | Q13315 | 1/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 6/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10061811 | 0.82 | MEN1 (0.69) | KMT2AMEN1TP53SMN1; SMN2GFER | |
| SCHEMBL5480161 | 0.80 | TP53 (0.67) | KMT2AMEN1TP53SMN1; SMN2GFER | |
| SCHEMBL18038469 | 0.79 | TP53 (1.00) | KMT2AMEN1TP53SMN1; SMN2GFER | |
| SCHEMBL8004824 | 0.79 | KMT2A (0.64) | KMT2AMEN1TP53SMN1; SMN2GFER | |
| SCHEMBL7941639 | 0.76 | ACHE (0.61) | KMT2AMEN1GFERMAPTGAA | |
| Hydrochloric Acid SCHEMBL7946348 | 0.75 | KMT2A (0.62) | KMT2AMEN1GFERMAPTPOLB | |
| SCHEMBL7944955 | 0.75 | BCHE (0.61) | KMT2AMEN1GFERMAPTGAA | |
| SCHEMBL5467891 | 0.74 | KMT2A (0.77) | KMT2AMEN1TP53SMN1; SMN2GFER | |
| SCHEMBL7935344 | 0.74 | KMT2A (0.68) | KMT2AMEN1TP53SMN1; SMN2GFER | |
| SCHEMBL16684277 | 0.74 | ACHE (0.66) | KMT2ABCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070253957-A1 | Substituted N-Aryl-1H-Pyrazolo[3,4-B]Quinolin-4-Amines and Analogs as Activators of Caspases and Inducers of Apoptosis | CYTOVIA, INC. (US) | 2007-11-01 | — | — | US | claimed |
| US-20070253957-A1 | Substituted N-Aryl-1H-Pyrazolo[3,4-B]Quinolin-4-Amines and Analogs as Activators of Caspases and Inducers of Apoptosis | CYTOVIA, INC. (US) | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070253957-A1 | Substituted N-Aryl-1H-Pyrazolo[3,4-B]Quinolin-4-Amines and Analogs as Activators of Caspases and Inducers of Apoptosis | CASP3, CASP7, CASP4 | KMT2A 2718/4885MEN1 3291/4885TP53 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.