SCHEMBL8005342

SCHEMBL8005342

C[S+]([O-])Cc1ccc(C(=O)c2ccc(Cl)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.48
MAPK1 P28482 1/20 0.48
HPGD P15428 1/20 0.47
VNN1 O95497 3/20 0.45
NPC1 O15118 3/20 0.44
RAB9A P51151 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
ALDH1A1 P00352 3/20 0.42
POLB P06746 2/20 0.42
GAA P10253 2/20 0.42
LMNA P02545 1/20 0.42
AGTR1 P30556 1/20 0.42
KDM4E B2RXH2 1/20 0.41
CTDSP1 Q9GZU7 1/20 0.41
ELANE P08246 1/20 0.41
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
FABP2 P12104 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19649630 0.85 IDO1 (0.42) RAB9AALDH1A1LMNAKDM4EMAOB
SCHEMBL8004317 0.83 SRD5A2 (0.46) SRD5A2MAPK1HPGDVNN1NPC1
SCHEMBL7995518 0.83 CA1 (0.42) SRD5A2HPGDVNN1CA1CA2
SCHEMBL8004323 0.83 MAPT (0.47) SRD5A2MAPK1HPGDRAB9ACA1
SCHEMBL8010797 0.83 LTA4H (0.46) MAPK1HPGDVNN1NPC1RAB9A
SCHEMBL8491716 0.80 ALDH1A1 (0.36) HPGDNPC1RAB9AL3MBTL1CA1
SCHEMBL8007764 0.79 SRD5A2 (0.44) SRD5A2MAPK1HPGDVNN1NPC1
SCHEMBL14756873 0.78 KMT2A (0.57) MAPK1HPGDRAB9AL3MBTL1ALDH1A1
SCHEMBL28399335 0.76 ALDH1A1 (0.65) SRD5A2MAPK1HPGDVNN1NPC1
SCHEMBL9065883 0.75 SRD5A2 (0.61) SRD5A2MAPK1HPGDVNN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6077866-A EXHIBIT POWERFUL INSECTICIDAL ACTION, ESPECIALLY AGAINST LEPIDOPTERA, COLEOPTERA AND SOIL INSECTS NIHON BAYER AGROCHEM K.K. (JP) 2000-06-20 US disclosed
EP-0742202-B1 Benzophenone hydrazone derivatives as insecticides BAYER AGROCHEM KK (JP) 1999-12-01 EP disclosed
EP-0766666-B1 BENZYLSULFIDE DERIVATIVE, PROCESS FOR ITS PRODUCTION AND PESTICIDE KUMIAI CHEMICAL INDUSTRY CO (JP) 1999-03-17 EP disclosed
US-5728699-A Benzylsulfide derivative, process for its production and pesticide KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1998-03-17 US disclosed
EP-0766666-A1 BENZYLSULFIDE DERIVATIVE, PROCESS FOR ITS PRODUCTION AND PESTICIDE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1997-04-09 EP disclosed
EP-0742202-A2 Benzophenone hydrazone derivatives as insecticides NIHON BAYER AGROCHEM K.K. (JP) 1996-11-13 EP disclosed
WO-1996033168-A1 BENZYLSULFIDE DERIVATIVE, PROCESS FOR ITS PRODUCTION AND PESTICIDE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1996-10-24 WO disclosed