Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL775752 | 0.85 | IDO1 (0.42) | LMNAMAOB | |
| SCHEMBL8007498 | 0.83 | LMNA (0.43) | LTA4HS1PR1CA1CA2LMNA | |
| SCHEMBL8004323 | 0.83 | MAPT (0.47) | CA1CA2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7995518 | 0.83 | CA1 (0.42) | CA1CA2LMNAALDH1A1HPGD | |
| SCHEMBL8005342 | 0.83 | SRD5A2 (0.48) | CA1CA2LMNAALDH1A1GAA | |
| SCHEMBL14756873 | 0.78 | KMT2A (0.57) | LMNASMN1; SMN2ALDH1A1GAAHPGD | |
| SCHEMBL3406790 | 0.76 | LMNA (0.65) | LTA4HS1PR1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9018906 | 0.75 | LTA4H (0.57) | LTA4HS1PR1CA1CA2LMNA | |
| SCHEMBL8577031 | 0.75 | LTA4H (0.57) | LTA4HS1PR1CA1CA2LMNA | |
| SCHEMBL238259 | 0.74 | LTA4H (0.73) | LTA4HCA1CA2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6077866-A | EXHIBIT POWERFUL INSECTICIDAL ACTION, ESPECIALLY AGAINST LEPIDOPTERA, COLEOPTERA AND SOIL INSECTS | NIHON BAYER AGROCHEM K.K. (JP) | 2000-06-20 | — | — | US | disclosed |
| EP-0742202-B1 | Benzophenone hydrazone derivatives as insecticides | BAYER AGROCHEM KK (JP) | 1999-12-01 | — | — | EP | disclosed |
| EP-0742202-A2 | Benzophenone hydrazone derivatives as insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1996-11-13 | — | — | EP | disclosed |