Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 10/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862584 | 0.80 | PDE4B (0.57) | PDE4B | |
| SCHEMBL29541597 | 0.78 | L3MBTL1 (0.46) | PDE4BL3MBTL1ALDH1A1LMNATSHR | |
| SCHEMBL2531010 | 0.77 | PDE4B (0.71) | PDE4B | |
| SCHEMBL8012386 | 0.73 | PDE4B (0.34) | PDE4BALDH1A1 | |
| SCHEMBL2531014 | 0.72 | PDE4B (0.68) | PDE4B | |
| SCHEMBL3094829 | 0.70 | HRH3 (0.60) | — | |
| SCHEMBL2529483 | 0.70 | L3MBTL1 (0.39) | PDE4BL3MBTL1ALDH1A1GPR119LMNA | |
| SCHEMBL14748429 | 0.70 | PTGS2 (0.43) | PDE4BL3MBTL1ALDH1A1GAA | |
| SCHEMBL7902874 | 0.68 | POLB (0.51) | L3MBTL1ALDH1A1LMNATSHRNPSR1 | |
| SCHEMBL14748452 | 0.68 | P2RX3 (0.35) | PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009111676-A2 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, INC (US) | 2009-09-11 | — | — | WO | disclosed |