Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7999666 | 0.89 | HRH1 (0.43) | SIGMAR1KCNH2 | |
| SCHEMBL8020139 | 0.85 | HRH1 (0.43) | SIGMAR1KCNH2 | |
| SCHEMBL8009255 | 0.84 | HRH1 (0.41) | SIGMAR1KCNH2 | |
| SCHEMBL8010890 | 0.84 | HRH1 (0.43) | SIGMAR1KCNH2 | |
| SCHEMBL7998241 | 0.82 | P2RX7 (0.48) | SIGMAR1KCNH2 | |
| SCHEMBL8010039 | 0.81 | HRH1 (0.42) | KCNH2 | |
| SCHEMBL7998338 | 0.81 | CTSK (0.44) | KCNH2 | |
| SCHEMBL8010524 | 0.81 | SLC6A4 (0.41) | KCNH2 | |
| SCHEMBL8018544 | 0.80 | HRH1 (0.41) | KCNH2 | |
| SCHEMBL8010463 | 0.79 | CHRNB2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000027394-A1 | ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | UNIVERSITY COLLEGE LONDON (GB) | 2000-05-18 | — | — | WO | disclosed |