Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18917606 | 0.89 | MMP8 (0.59) | MMP8ALDH1A1TP53MAPK1L3MBTL1 | |
| SCHEMBL27744395 | 0.86 | SMN1; SMN2 (0.43) | MMP8ALDH1A1TP53MAPK1L3MBTL1 | |
| SCHEMBL14184715 | 0.85 | EPHX2 (0.51) | MMP8MAPK1L3MBTL1TSHRTDP1 | |
| SCHEMBL17604992 | 0.84 | ALDH1A1 (0.63) | MMP8ALDH1A1TP53MAPK1L3MBTL1 | |
| SCHEMBL4081032 | 0.84 | PPARG (0.44) | MMP8SMN1; SMN2 | |
| SCHEMBL4334347 | 0.81 | SMN1; SMN2 (0.40) | MMP8ALDH1A1TP53MAPK1L3MBTL1 | |
| SCHEMBL20543616 | 0.81 | MMP8 (0.52) | MMP8ALDH1A1TP53MAPK1L3MBTL1 | |
| SCHEMBL2672677 | 0.81 | MMP8 (0.56) | MMP8ALDH1A1TP53MAPK1L3MBTL1 | |
| SCHEMBL2422171 | 0.81 | MMP8 (0.52) | MMP8ALDH1A1TP53MAPK1L3MBTL1 | |
| SCHEMBL5475645 | 0.81 | MMP8 (0.52) | MMP8ALDH1A1TP53MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6099625-A | Ink composition | ZENECA LIMITED (GB) | 2000-08-08 | — | — | US | disclosed |
| EP-0823927-A2 | INK COMPOSITION | ZENECA LIMITED (GB) | 1998-02-18 | — | — | EP | disclosed |
| WO-1996034916-A2 | INK COMPOSITION | ZENECA LIMITED (GB) | 1996-11-07 | — | — | WO | disclosed |