SCHEMBL4334347

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13810212	0.86	LOXL2 (0.41)	SMN1; SMN2MMP8L3MBTL1MAPK1TSHR
	SCHEMBL4081032	0.86	PPARG (0.44)	SMN1; SMN2MMP8
	Hydrochloric Acid SCHEMBL4332232	0.85	LOXL2 (0.40)	SMN1; SMN2MMP8L3MBTL1MAPK1TSHR
	SCHEMBL4332258	0.85	GRIA2 (0.42)	MMP8L3MBTL1MAPK1TSHRTDP1
	SCHEMBL4329899	0.85	MMP8 (0.39)	SMN1; SMN2MMP8L3MBTL1MAPK1TSHR
	SCHEMBL4332255	0.85	GRIA2 (0.42)	MMP8L3MBTL1MAPK1TSHRTDP1
	SCHEMBL13810945	0.84	L3MBTL1 (0.44)	MMP8L3MBTL1MAPK1TSHRTDP1
	SCHEMBL13819361	0.84	CYP4F2 (0.41)	MMP8L3MBTL1MAPK1TSHRTDP1
	SCHEMBL4332256	0.84	MMP8 (0.38)	SMN1; SMN2MMP8L3MBTL1MAPK1TSHR
	SCHEMBL1857286	0.83	LMNA (0.46)	SMN1; SMN2MMP8TSHRALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.