SCHEMBL18917606

SCHEMBL18917606

CCOC(=O)C(Cc1cccc(CC(C(=O)OCC)C(=O)OCC)c1)C(=O)OCC

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.59
ALDH1A1 P00352 3/20 0.56
TP53 P04637 1/20 0.56
TDP1 Q9NUW8 4/20 0.54
MAPK1 P28482 3/20 0.54
L3MBTL1 Q9Y468 3/20 0.54
TSHR P16473 3/20 0.54
NPY1R P25929 1/20 0.48
NPY2R P49146 1/20 0.48
PKM P14618 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.43
CYP4F2 P78329 1/20 0.43
CYP4A11 Q02928 1/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
PIN1 Q13526 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20543616 0.92 MMP8 (0.52) MMP8ALDH1A1TP53TDP1MAPK1
SCHEMBL17604992 0.91 ALDH1A1 (0.63) MMP8ALDH1A1TP53TDP1MAPK1
SCHEMBL18926557 0.91 EPHX2 (0.52) MMP8ALDH1A1TP53TDP1MAPK1
SCHEMBL2422171 0.89 MMP8 (0.52) MMP8ALDH1A1TP53TDP1MAPK1
SCHEMBL5475645 0.89 MMP8 (0.52) MMP8ALDH1A1TP53TDP1MAPK1
SCHEMBL2672677 0.89 MMP8 (0.56) MMP8ALDH1A1TP53TDP1MAPK1
SCHEMBL8007724 0.89 MMP8 (0.52) MMP8ALDH1A1TP53TDP1MAPK1
SCHEMBL2672357 0.87 ALDH1A1 (0.60) MMP8ALDH1A1TP53TDP1MAPK1
SCHEMBL165382 0.87 MMP8 (0.76) MMP8ALDH1A1TP53TDP1MAPK1
SCHEMBL6714650 0.85 HTR2A (0.55) MMP8ALDH1A1TP53TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250025855-A1 EMM-41 COMPOSITION, METHODS OF MAKING AND USES THEREOF ExxonMobil Technology and Engineering Company 2025-01-23 US disclosed
US-20250025854-A1 EMM-41 COMPOSITION, METHODS OF MAKING AND USES THEREOF ExxonMobil Technology and Engineering Company 2025-01-23 US disclosed
US-12161990-B2 EMM-41 composition, methods of making and uses thereof ExxonMobil Technology and Engineering Company (US) 2024-12-10 US disclosed
US-20220023827-A1 EMM-41 Composition, Methods of Making and Uses Thereof EXXONMOBIL RES & ENG CO (US) 2022-01-27 US disclosed
US-20220023827-A1 EMM-41 Composition, Methods of Making and Uses Thereof EXXONMOBIL RES & ENG CO (US) 2022-01-27 US disclosed
EP-3383796-B1 EMM-28, A NOVEL SYNTHETIC CRYSTALLINE MATERIAL, ITS PREPARATION AND USE EXXONMOBIL RES & ENG CO (US) 2020-09-16 EP disclosed
US-10597300-B2 EMM-28, a novel synthetic crystalline material, its preparation and use EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-03-24 US disclosed
US-20190218106-A1 EMM-28, A NOVEL SYNTHETIC CRYSTALLINE MATERIAL, ITS PREPARATION AND USE EXXONMOBIL RES & ENG CO (US) 2019-07-18 US disclosed
US-20190218106-A1 EMM-28, A NOVEL SYNTHETIC CRYSTALLINE MATERIAL, ITS PREPARATION AND USE EXXONMOBIL RES & ENG CO (US) 2019-07-18 US disclosed
US-10252918-B2 EMM-28, a novel synthetic crystalline material, its preparation and use EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2019-04-09 US disclosed
US-10252918-B2 EMM-28, a novel synthetic crystalline material, its preparation and use EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2019-04-09 US disclosed
EP-3383796-A1 EMM-28, A NOVEL SYNTHETIC CRYSTALLINE MATERIAL, ITS PREPARATION AND USE Exxonmobil Research And Engineering Company (US) 2018-10-10 EP disclosed
US-20170158521-A1 EMM-28, A NOVEL SYNTHETIC CRYSTALLINE MATERIAL, ITS PREPARATION AND USE EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2017-06-08 US disclosed
US-20170158521-A1 EMM-28, A NOVEL SYNTHETIC CRYSTALLINE MATERIAL, ITS PREPARATION AND USE EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2017-06-08 US disclosed
WO-2017095705-A1 EMM-28, A NOVEL SYNTHETIC CRYSTALLINE MATERIAL, ITS PREPARATION AND USE EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2017-06-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220023827-A1 EMM-41 Composition, Methods of Making and Uses Thereof CD14, CD68, MASP2 MMP8 88/4885ALDH1A1 4549/4885TP53 721/4885
US-20250025855-A1 EMM-41 COMPOSITION, METHODS OF MAKING AND USES THEREOF CD14, CD68, MASP2 MMP8 88/4885ALDH1A1 4549/4885TP53 721/4885
US-12161990-B2 EMM-41 composition, methods of making and uses thereof CD14, CD68, MASP2 MMP8 88/4885ALDH1A1 4549/4885TP53 721/4885
US-10597300-B2 EMM-28, a novel synthetic crystalline material, its preparation and use CD14, ERG28, DAP3 MMP8 437/4885ALDH1A1 4842/4885TP53 544/4885
US-10252918-B2 EMM-28, a novel synthetic crystalline material, its preparation and use CD14, ERG28, DAP3 MMP8 437/4885ALDH1A1 4842/4885TP53 544/4885
US-20250025854-A1 EMM-41 COMPOSITION, METHODS OF MAKING AND USES THEREOF CD14, CD68, MASP2 MMP8 88/4885ALDH1A1 4549/4885TP53 721/4885
US-20170158521-A1 EMM-28, A NOVEL SYNTHETIC CRYSTALLINE MATERIAL, ITS PREPARATION AND USE CD14, ERG28, DAP3 MMP8 437/4885ALDH1A1 4842/4885TP53 544/4885
US-20190218106-A1 EMM-28, A NOVEL SYNTHETIC CRYSTALLINE MATERIAL, ITS PREPARATION AND USE CD14, ERG28, DAP3 MMP8 437/4885ALDH1A1 4842/4885TP53 544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.