Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CASR | P41180 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL444179 | 0.81 | CASR (0.74) | ALDH1A1HTTALOX12MAPTCASR | |
| SCHEMBL8775391 | 0.81 | ALDH1A1 (0.74) | ALDH1A1HTTALOX12MAPTCASR | |
| SCHEMBL4983929 | 0.79 | KDM1A (0.47) | LMNA | |
| Bromide SCHEMBL5449604 | 0.77 | KDM1A (0.46) | LMNAP2RX7 | |
| SCHEMBL8007408 | 0.75 | CASR (0.64) | HTTCASRLMNAKCNQ2KMT2A | |
| SCHEMBL8011444 | 0.74 | LMNA (0.47) | ALDH1A1HTTALOX12MAPTCASR | |
| Hydrochloric Acid SCHEMBL7995663 | 0.74 | CASR (0.62) | HTTCASRLMNAKCNQ2KMT2A | |
| SCHEMBL4314850 | 0.72 | CYP1A2 (0.48) | ALDH1A1HTTMAPTLMNAMEN1 | |
| SCHEMBL8007374 | 0.72 | CASR (0.60) | HTTCASRKCNQ2MEN1KMT2A | |
| SCHEMBL4268472 | 0.71 | KMT2A (0.60) | ALDH1A1HTTALOX12MAPTCASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060484-A | Anti-viral method | ELI LILLY AND COMPANY (US) | 2000-05-09 | — | — | US | disclosed |
| EP-0806205-A2 | Urea, thiourea and guanidine compounds and their use as anti-viral agents | ELI LILLY AND COMPANY (US) | 1997-11-12 | — | — | EP | disclosed |