SCHEMBL8007977

SCHEMBL8007977

C=CC(=O)OC(CCC)[SiH](OCCC)OCCC

nearest known ligand 0.40

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.40
HPGD P15428 1/20 0.40
ALDH1A1 P00352 3/20 0.32
TP53 P04637 2/20 0.32
HIF1A Q16665 2/20 0.32
CYP3A4 P08684 1/20 0.32
HSD17B10 Q99714 1/20 0.32
THRB P10828 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2853098 0.89 TSHR (0.37) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL139101 0.89 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL193209 0.83 TSHR (0.38) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28030112 0.80 TSHR (0.40) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL140102 0.79 TSHR (0.50) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL3750794 0.78 TSHR (0.39) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28217128 0.75 TSHR (0.38) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL28214426 0.75 TSHR (0.33) TSHRHPGD
SCHEMBL143214 0.75 TSHR (0.36) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL12468571 0.74 TSHR (0.46) TSHRHPGDALDH1A1CYP3A4THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12337286-B2 Composite semipermeable membrane NITTO DENKO CORPORATION (JP) 2025-06-24 US disclosed
CN-115851067-A Coating composition, exterior wall, coating composition for building exterior, and laminate 日信化学工业株式会社 2023-03-28 CN disclosed
US-20230058893-A1 COMPOSITE SEMIPERMEABLE MEMBRANE NITTO DENKO CORPORATION (JP) 2023-02-23 US disclosed
EP-4074411-A1 COMPOSITE SEMI-PERMEABLE MEMBRANE Nitto Denko Corporation (JP) 2022-10-19 EP disclosed
CN-114957568-A Transparent coating composition, transparent coating film, and article having the film 日信化学工业株式会社 2022-08-30 CN disclosed
CN-114854271-A Coating composition, coating film and article having the coating film 日信化学工业株式会社 2022-08-05 CN disclosed
CN-114806316-A Exterior wall, coating composition for building exterior, and laminate 日信化学工业株式会社 2022-07-29 CN disclosed
CN-114806315-A Coating composition for furniture and building interior, and laminate 日信化学工业株式会社 2022-07-29 CN disclosed
CN-113527595-B Functionalized organic silicon resin and preparation method and application thereof 中国科学院长春应用化学研究所 2022-06-07 CN disclosed
CN-113527595-A Functionalized organic silicon resin and preparation method and application thereof 中国科学院长春应用化学研究所 2021-10-22 CN disclosed
CN-113454133-A Emulsion composition of (meth) acrylic silicone resin, fiber treatment agent containing the same, and fiber treated with the fiber treatment agent 日信化学工业株式会社 2021-09-28 CN disclosed
WO-2021117631-A1 COMPOSITE SEMI-PERMEABLE MEMBRANE 日東電工株式会社 2021-06-17 WO disclosed
CN-111465645-A Rubber composition and pneumatic tire 株式会社普利司通 2020-07-28 CN disclosed
CN-108602987-B Rubber composition and tire 株式会社普利司通 2020-07-21 CN disclosed
CN-111344453-A Coating agent for leather and leather formed with the same 日信化学工业株式会社 2020-06-26 CN disclosed
EP-0695783-B1 Low solvent content type-resin composition, coating composition containing such resin composition and process for coating such coating composition MAZDA MOTOR (JP) 2000-02-02 EP disclosed
US-5650475-A VINYL POLYMERS WITH BLOCKED CARBOXY, SILANOL, EPOXY, HYDROLYZED SILYL AND ACID ANHYDRIDES IN SOLVENTS MAZDA MOTOR CORPORATION (JP) 1997-07-22 US disclosed
EP-0695783-A2 Low solvent content type-resin composition, coating composition containing such resin composition and process for coating such coating composition Mazda Motor Corporation (JP) 1996-02-07 EP disclosed
EP-0688841-A2 Low solvent content type-resin composition, coating composition containing such resin composition and process for coating such coating composition MAZDA MOTOR CORPORATION (JP) 1995-12-27 EP disclosed