Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093319 | 0.85 | TSHR (0.42) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL28030112 | 0.84 | TSHR (0.40) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL193209 | 0.81 | TSHR (0.38) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL2853098 | 0.79 | TSHR (0.37) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL8007977 | 0.78 | TSHR (0.40) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL524941 | 0.77 | TSHR (0.36) | TSHRALDH1A1CYP3A4SMN1; SMN2HSD17B10 | |
| SCHEMBL8648130 | 0.76 | TSHR (0.42) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL3175840 | 0.75 | ALDH1A1 (0.39) | TSHRTHRBALDH1A1 | |
| SCHEMBL11442003 | 0.75 | TSHR (0.39) | TSHRHPGDTHRBALDH1A1TP53 | |
| SCHEMBL9545994 | 0.75 | TSHR (0.45) | TSHRHPGDTHRBALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0495936-A4 | METHOD FOR ENHANCING THE STRENGTH OF A GLASS CONTAINER AND STRENGTH ENHANCED GLASS CONTAINER | — | 1993-03-17 | — | — | EP | claimed |
| EP-0495936-A1 | METHOD FOR ENHANCING THE STRENGTH OF A GLASS CONTAINER AND STRENGTH ENHANCED GLASS CONTAINER | ADVANCED GLASS TREATMENT SYSTEMS (US) | 1992-07-29 | — | — | EP | claimed |
| WO-1991019606-A1 | METHOD FOR ENHANCING THE STRENGTH OF A GLASS CONTAINER AND STRENGTH ENHANCED GLASS CONTAINER | ADVANCED GLASS TREATMENT SYSTEMS (US) | 1991-12-26 | — | — | WO | claimed |
| EP-4725470-A1 | CURABLE DENTAL COMPOSITION | Kuraray Noritake Dental Inc. (JP) | 2026-04-15 | — | — | EP | disclosed |
| US-20250032366-A1 | DENTAL CURABLE COMPOSITION | KURARAY NORITAKE DENTAL INC. (JP) | 2025-01-30 | — | — | US | disclosed |
| US-20250009607-A1 | DENTAL COMPOSITION AND METHOD OF PRODUCTION THEREOF, AND SURFACE-TREATED FILLER FOR DENTAL USE | KURARAY NORITAKE DENTAL INC. (JP) | 2025-01-09 | — | — | US | disclosed |
| WO-2024253204-A1 | CURABLE DENTAL COMPOSITION | クラレノリタケデンタル株式会社 | 2024-12-12 | — | — | WO | disclosed |
| EP-4464301-A1 | DENTAL COMPOSITION, METHOD FOR MANUFACTURING SAME, AND DENTAL SURFACE-TREATED FILLER | Kuraray Noritake Dental Inc. (JP) | 2024-11-20 | — | — | EP | disclosed |
| EP-4445891-A1 | DENTAL CURABLE COMPOSITION | Kuraray Noritake Dental Inc. (JP) | 2024-10-16 | — | — | EP | disclosed |
| WO-2024090337-A1 | METHOD FOR PRODUCING ORGANOSILICON COMPOUND HAVING (METH)ACRYLOXY GROUP, AND ORGANOSILICON COMPOUND HAVING ACRYLOXY GROUP | 信越化学工業株式会社 | 2024-05-02 | — | — | WO | disclosed |
| WO-2023136337-A1 | DENTAL COMPOSITION, METHOD FOR MANUFACTURING SAME, AND DENTAL SURFACE-TREATED FILLER | クラレノリタケデンタル株式会社 | 2023-07-20 | — | — | WO | disclosed |
| US-7834120-B2 | Monofunctional monomer having cage oligosiloxane structure and method of making | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-11-16 | — | — | US | disclosed |
| EP-1645560-B1 | Monofunctional monomer having cage oligosiloxane structure and method of making | SHINETSU CHEMICAL CO (JP) | 2008-05-28 | — | — | EP | disclosed |
| EP-1645560-A1 | Monofunctional monomer having cage oligosiloxane structure and method of making | Shin-Etsu Chemical Co., Ltd. (JP) | 2006-04-12 | — | — | EP | disclosed |
| US-20060074213-A1 | Monofunctional monomer having cage oligosiloxane structure and method of making | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2006-04-06 | — | — | US | disclosed |
| US-5852153-A | Trimethylsiloxy group-containing polysiloxane and a process for producing the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-12-22 | — | — | US | disclosed |
| US-5693735-A | Trimethylsiloxy group-containing polysiloxane and a process for producing the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| EP-0495936-A4 | METHOD FOR ENHANCING THE STRENGTH OF A GLASS CONTAINER AND STRENGTH ENHANCED GLASS CONTAINER | — | 1993-03-17 | — | — | EP | disclosed |
| EP-0495936-A1 | METHOD FOR ENHANCING THE STRENGTH OF A GLASS CONTAINER AND STRENGTH ENHANCED GLASS CONTAINER | ADVANCED GLASS TREATMENT SYSTEMS (US) | 1992-07-29 | — | — | EP | disclosed |
| WO-1991019606-A1 | METHOD FOR ENHANCING THE STRENGTH OF A GLASS CONTAINER AND STRENGTH ENHANCED GLASS CONTAINER | ADVANCED GLASS TREATMENT SYSTEMS (US) | 1991-12-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250032366-A1 | DENTAL CURABLE COMPOSITION | H1-0, COL1A1, CHAF1B | TSHR 4352/4885HPGD 2520/4885THRB 3473/4885 |
| US-20250009607-A1 | DENTAL COMPOSITION AND METHOD OF PRODUCTION THEREOF, AND SURFACE-TREATED FILLER FOR DENTAL USE | CAD, SEM1, CAPZA1 | TSHR 3083/4885HPGD 1522/4885THRB 3579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.