SCHEMBL2853098

SCHEMBL2853098

C=CC(=O)OC(CCC)[SiH](OCC)OCC

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
HPGD P15428 1/20 0.37
THRB P10828 2/20 0.32
THRA P10827 1/20 0.30
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8007977 0.89 TSHR (0.40) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL143214 0.86 TSHR (0.36) TSHRHPGDTHRBALDH1A1TP53
SCHEMBL193209 0.85 TSHR (0.38) TSHRHPGDTHRBTHRAALDH1A1
SCHEMBL28030112 0.81 TSHR (0.40) TSHRHPGDTHRBTHRAALDH1A1
SCHEMBL3750794 0.79 TSHR (0.39) TSHRHPGDTHRBTHRAALDH1A1
SCHEMBL3341050 0.79 TSHR (0.33) TSHRALDH1A1CYP3A4
SCHEMBL28562846 0.78 TSHR (0.36) TSHRHPGDTHRB
SCHEMBL555328 0.77 ALDH1A1 (0.36) TSHRTHRBALDH1A1
SCHEMBL139101 0.77 TSHR (0.41) TSHRHPGDTHRBTHRAALDH1A1
SCHEMBL28214426 0.76 TSHR (0.33) TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115772379-A UV (ultraviolet) delayed curing double-component polyurethane adhesive and preparation method thereof 韦尔通(厦门)科技股份有限公司 2023-03-10 CN claimed
US-12638716-B2 Liquid crystal display apparatus Wuxi Hengxin Optoelectronic Materials Co., Ltd. (CN) 2026-05-26 US disclosed
EP-4725470-A1 CURABLE DENTAL COMPOSITION Kuraray Noritake Dental Inc. (JP) 2026-04-15 EP disclosed
EP-4726006-A1 PRESSURE-SENSITIVE ADHESIVE SHEET Nitto Denko Corporation (JP) 2026-04-15 EP disclosed
US-12591084-B2 Polarizing plate and optical display apparatus Wuxi Hengxin Optoelectronic Materials Co., Ltd. (CN) 2026-03-31 US disclosed
US-20260085145-A1 CURABLE RESIN, CURABLE RESIN COMPOSITION, AND CURED ARTICLE DAINIPPON INK & CHEMICALS (JP) 2026-03-26 US disclosed
US-20260013767-A1 ADHESIVE ELECTRODE FOR BIOSIGNAL ACQUISITION AND BIOSENSOR NITTO DENKO CORP (JP) 2026-01-15 US disclosed
US-12497518-B2 Resin-coated metal powder, method for producing same and aqueous coating composition using same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-12-16 US disclosed
US-20250339075-A1 BIOLOGICAL SENSOR NITTO DENKO CORP (JP) 2025-11-06 US disclosed
EP-4644505-A1 ADHESIVE COMPOSITION, CURED BODY, AND ADHESIVE FOR ELECTRONIC DEVICES Sekisui Chemical Co., Ltd. (JP) 2025-11-05 EP disclosed
US-20110293844-A1 PAINT COMPOSITION AND COATING FILM FORMATION METHOD KANSAI PAINT CO., LTD. (JP) 2011-12-01 US disclosed
US-7834120-B2 Monofunctional monomer having cage oligosiloxane structure and method of making SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-11-16 US disclosed
US-20100040806-A1 CELLULOSE ESTER OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY USING THE CELLULOSE ESTER OPTICAL FILM, AND METHOD FOR PRODUCING CELLULOSE ESTER OPTICAL FILM KONICA MINOLTA OPTO, INC. (JP) 2010-02-18 US disclosed
WO-2009075392-A1 COATING COMPOSITION AND METHOD FOR FORMING MULTILAYER COATING FILM KANSAI PAINT CO., LTD. (JP) 2009-06-18 WO disclosed
US-20090135345-A1 Polarizing Plate Protective Film, Film Producing Method, Polarizing Plate, and Liquid Crystal Display KONICA MINOLTA OPTO, INC. (JP) 2009-05-28 US disclosed
EP-1645560-B1 Monofunctional monomer having cage oligosiloxane structure and method of making SHINETSU CHEMICAL CO (JP) 2008-05-28 EP disclosed
WO-2008035622-A1 COATING COMPOSITION AND METHOD FOR FORMING MULTILAYER TOPCOAT FILM KANSAI PAINT CO., LTD. (JP) 2008-03-27 WO disclosed
EP-1645560-A1 Monofunctional monomer having cage oligosiloxane structure and method of making Shin-Etsu Chemical Co., Ltd. (JP) 2006-04-12 EP disclosed
US-20060074213-A1 Monofunctional monomer having cage oligosiloxane structure and method of making SHIN-ETSU CHEMICAL CO., LTD. (JP) 2006-04-06 US disclosed
WO-1999042078-A2 HARDENABLE DENTAL MATERIAL AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1999-08-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260085145-A1 CURABLE RESIN, CURABLE RESIN COMPOSITION, AND CURED ARTICLE MAT1A, CAPZA1, CDH1 TSHR 3836/4885HPGD 3014/4885THRB 1923/4885
US-12591084-B2 Polarizing plate and optical display apparatus NECTIN4, FZD7, ATG13 TSHR 3070/4885HPGD 4685/4885THRB 4588/4885
US-12638716-B2 Liquid crystal display apparatus VCL, NECTIN4, DVL1 TSHR 2486/4885HPGD 4598/4885THRB 3104/4885
US-20260013767-A1 ADHESIVE ELECTRODE FOR BIOSIGNAL ACQUISITION AND BIOSENSOR ICAM1, CUTA, L1CAM TSHR 4231/4885HPGD 856/4885THRB 2241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.