Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8018100 | 0.66 | CYP1A2 (0.37) | CYP1A2CYP3A4CYP2D6MEN1NPC1 | |
| Hydrochloric Acid SCHEMBL29227043 | 0.60 | ACHE (0.45) | MEN1NPC1USP2RAB9AKMT2A | |
| SCHEMBL7751174 | 0.59 | ADORA2B (0.30) | — | |
| SCHEMBL9278291 | 0.59 | CYP3A4 (0.30) | CYP3A4 | |
| SCHEMBL1947169 | 0.59 | SMN1; SMN2 (0.40) | MEN1NPC1RAB9AKMT2A | |
| SCHEMBL14364186 | 0.59 | ADORA2B (0.30) | — | |
| Hydrochloric Acid SCHEMBL59757 | 0.59 | SMN1; SMN2 (0.43) | MEN1NPC1RAB9AKMT2A | |
| Iodide SCHEMBL4057555 | 0.58 | — | — | |
| Hydrochloric Acid SCHEMBL7695773 | 0.58 | CYP1A2 (0.33) | CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL573670 | 0.58 | ACHE (0.42) | HDAC8MEN1NPC1USP2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000037400-A1 | HALOGENATION IN IONIC LIQUIDS | INEOS CHLOR LIMITED (GB) | 2000-06-29 | — | — | WO | disclosed |