Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29227043 | 0.67 | ACHE (0.45) | RAB9AMEN1NPC1USP2KMT2A | |
| Hydrochloric Acid SCHEMBL8023885 | 0.66 | CYP3A4 (0.34) | CYP1A2CYP3A4CYP2D6MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8008095 | 0.66 | HDAC8 (0.44) | CYP1A2CYP3A4CYP2D6RAB9AMEN1 | |
| SCHEMBL573670 | 0.64 | ACHE (0.42) | RAB9AMEN1NPC1USP2KMT2A | |
| Iodide SCHEMBL14765236 | 0.63 | ACHE (0.41) | RAB9AMEN1NPC1USP2KMT2A | |
| SCHEMBL8027716 | 0.63 | CYP3A4 (0.35) | CYP1A2CYP3A4CYP2D6MEN1KMT2A | |
| Bromide SCHEMBL31481338 | 0.63 | ACHE (0.41) | RAB9AMEN1NPC1USP2KMT2A | |
| SCHEMBL1848658 | 0.62 | — | — | |
| SCHEMBL28687416 | 0.62 | ALDH1A1 (0.34) | CYP1A2CYP3A4CYP2D6PDE4BPDE4D | |
| Hydrochloric Acid SCHEMBL1077570 | 0.61 | CA1 (0.40) | MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000037400-A1 | HALOGENATION IN IONIC LIQUIDS | INEOS CHLOR LIMITED (GB) | 2000-06-29 | — | — | WO | disclosed |