SCHEMBL8008236

SCHEMBL8008236

OCCOOC=Cc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAM P19021 1/20 0.41
ALDH1A1 P00352 2/20 0.41
RECQL P46063 2/20 0.41
MAOB P27338 1/20 0.38
IDO1 P14902 2/20 0.37
AKR1B10 O60218 1/20 0.37
AKR1B1 P15121 1/20 0.37
LMNA P02545 2/20 0.36
HDAC3 O15379 1/20 0.36
TNKS O95271 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC10 Q969S8 1/20 0.36
HDAC11 Q96DB2 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
TNKS2 Q9H2K2 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1891350 0.80 ALDH1A1 (0.43) PAMALDH1A1RECQLMAOBIDO1
SCHEMBL367481 0.76 MAOB (0.55) ALDH1A1RECQLMAOBIDO1LMNA
SCHEMBL7060730 0.74 MEN1 (0.40) PAMALDH1A1RECQLMAOBIDO1
SCHEMBL25430836 0.74 MEN1 (0.40) PAMALDH1A1RECQLMAOBIDO1
SCHEMBL7058227 0.74 MEN1 (0.40) PAMALDH1A1RECQLMAOBIDO1
SCHEMBL8021987 0.73 MEN1 (0.46) ALDH1A1MAOBIDO1LMNAMAPT
SCHEMBL9302860 0.73 MAOB (0.54) PAMALDH1A1RECQLMAOBIDO1
Ethylene Glycol SCHEMBL27581622 0.72 TRPA1 (0.45) PAMALDH1A1MAOBIDO1CYP1A2
SCHEMBL367479 0.72 MAOB (0.50) ALDH1A1RECQLMAOBIDO1LMNA
SCHEMBL367480 0.72 MAOB (0.50) ALDH1A1RECQLMAOBIDO1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6139998-A OPTICAL ELEMENTS WITH POLYMER RESIN ON SUBSTRATES INNER SURFACE OF THE CYLINDRICAL SUBSTRATE IS NOT MORE THAN 0.5 .MU.M. THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR EMPLOYING THE SUBSTRATE IS KONICA CORPORATION (JP) 2000-10-31 US disclosed