Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CD69 | Q07108 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8011044 | 0.90 | DGAT1 (0.39) | DGAT1PPARASMN1; SMN2ELANECD69 | |
| SCHEMBL4495832 | 0.77 | KDM1A (0.42) | ESR1ESR2DGAT1FFAR1MAPK1 | |
| SCHEMBL4495829 | 0.77 | KDM1A (0.42) | ESR1ESR2DGAT1FFAR1MAPK1 | |
| SCHEMBL3706515 | 0.76 | DGAT1 (0.45) | DGAT1ALDH1A1TDP1 | |
| SCHEMBL3411510 | 0.74 | ESR1 (0.49) | ESR1ESR2DGAT1ALDH1A1 | |
| SCHEMBL3749487 | 0.74 | ESR1 (0.49) | ESR1ESR2DGAT1ALDH1A1 | |
| SCHEMBL30671685 | 0.68 | CYP2C19 (0.33) | POLBPPARASMN1; SMN2ELANECD69 | |
| SCHEMBL809019 | 0.68 | KDM5A (0.52) | CYP2C19MEN1MAPK1KMT2A | |
| SCHEMBL24451272 | 0.67 | HRH3 (0.39) | ESR1SMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL17563595 | 0.66 | CYP11B2 (0.40) | POLBAPEX1KARS1PPARARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103688-A | TERT-BUTYL SUBSTITUTED INDAN DERIVATIVES | FIRMENICH SA (CH) | 2000-08-15 | — | — | US | disclosed |
| US-5552379-A | FLORAL, FOR COSMETICS AND HOUSEHOLD ITEMS | FIRMENICH SA (CH) | 1996-09-03 | — | — | US | disclosed |