Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009555 | 1.00 | TSHR (0.41) | TSHRTBXAS1ALDH1A1GAAPOLB | |
| SCHEMBL30528 | 0.82 | CYP2C9 (0.51) | TBXAS1ALDH1A1MAPTKMT2AHTT | |
| SCHEMBL30530 | 0.82 | CYP2C9 (0.51) | TBXAS1ALDH1A1MAPTKMT2AHTT | |
| Iodide SCHEMBL3761279 | 0.81 | CYP2C9 (0.50) | TBXAS1ALDH1A1MAPTKMT2AHTT | |
| SCHEMBL2581810 | 0.80 | CYP1A2 (0.43) | TSHRALDH1A1KMT2AHTTCYP2C9 | |
| SCHEMBL5339952 | 0.80 | TBXAS1 (0.48) | TSHRTBXAS1ALDH1A1KMT2A | |
| SCHEMBL15301308 | 0.79 | ALDH1A1 (0.48) | ALDH1A1KDM4EMAPTTDP1KMT2A | |
| SCHEMBL7634733 | 0.79 | TRPA1 (0.42) | TSHRTBXAS1TDP1CYP2C9AKR1C3 | |
| SCHEMBL8615571 | 0.79 | MEN1 (0.42) | ALDH1A1KMT2ACYP1A2AKR1C3 | |
| SCHEMBL1921017 | 0.79 | CTBP2 (0.44) | ALDH1A1TDP1KMT2AL3MBTL1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6159654-A | Negative photosensitive polymer composition of a thermosetting polymer precursor curable by cyclodehydration upon heating | KABUSHIKI KAISHA TOSHIBA (JP) | 2000-12-12 | — | — | US | claimed |