Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6184056 | 0.91 | KDM4E (0.46) | CA1CA2CA12CA9DNM1 | |
| SCHEMBL9702686 | 0.87 | DNM1 (0.46) | CA1CA2CA12CA9DNM1 | |
| SCHEMBL13609675 | 0.87 | DNM1 (0.46) | CA1CA2CA12CA9DNM1 | |
| SCHEMBL7241259 | 0.87 | ALDH1A1 (0.48) | CA1CA2CA12CA9DNM1 | |
| SCHEMBL3760523 | 0.85 | DNM1 (0.44) | CA1CA2CA12CA9DNM1 | |
| Hydrochloric Acid SCHEMBL10442360 | 0.85 | DNM1 (0.44) | CA1CA2CA12CA9DNM1 | |
| SCHEMBL3760526 | 0.85 | DNM1 (0.44) | CA1CA2CA12CA9DNM1 | |
| SCHEMBL78355 | 0.84 | KDM4E (0.59) | DNM1KDM4EMEN1KMT2AHTT | |
| SCHEMBL14997848 | 0.84 | DNM1 (0.43) | CA1CA2CA12CA9DNM1 | |
| SCHEMBL21499 | 0.84 | DNM1 (0.43) | CA1CA2CA12CA9DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000063219-A1 | PLATINUM COMPLEXES FOR THE TREATMENT OF CANCER | UNITECH PHARMACEUTICALS, INC. (US) | 2000-10-26 | — | — | WO | claimed |
| US-6130245-A | Dinuclear platinum complexes as cisplatin analogs for cancer treatment | UNITECH PHARMACEUTICALS, INC. (US) | 2000-10-10 | — | — | US | claimed |
| CN-103435657-A | Organic metal platinum compound with anti-cancer effect, and synthesis method thereof | UNIV DEZHOU | 2013-12-11 | — | — | CN | disclosed |
| EP-1468032-B1 | ALKYLAMINO OXAMIDES AS LOW ODOR NON FUGITIVE CATALYSTS FOR THE PRODUCTION OF POLYURETHANES | MOMENTIVE PERFORMANCE MAT INC (US) | 2009-10-21 | — | — | EP | disclosed |
| WO-2000063219-A1 | PLATINUM COMPLEXES FOR THE TREATMENT OF CANCER | UNITECH PHARMACEUTICALS, INC. (US) | 2000-10-26 | — | — | WO | disclosed |
| US-6130245-A | Dinuclear platinum complexes as cisplatin analogs for cancer treatment | UNITECH PHARMACEUTICALS, INC. (US) | 2000-10-10 | — | — | US | disclosed |