SCHEMBL9702686

SCHEMBL9702686

CN(C)CCNC(=O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.46
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA12 O43570 1/20 0.45
CA9 Q16790 1/20 0.45
KDM4E B2RXH2 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
PRMT3 O60678 1/20 0.40
CARM1 Q86X55 1/20 0.40
PRMT6 Q96LA8 1/20 0.40
PRMT1 Q99873 1/20 0.40
PRMT8 Q9NR22 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MAPK1 P28482 1/20 0.40
ALDH1A1 P00352 3/20 0.39
MAPT P10636 1/20 0.39
USP2 O75604 1/20 0.38
GLA P06280 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10442360 0.98 DNM1 (0.44) DNM1CA1CA2CA12CA9
SCHEMBL8009723 0.87 CA1 (0.50) DNM1CA1CA2CA12CA9
SCHEMBL9702900 0.86 KDM4E (0.54) DNM1KDM4EMEN1KMT2AHTT
SCHEMBL13609675 0.81 DNM1 (0.46) DNM1CA1CA2CA12CA9
SCHEMBL1414877 0.80
SCHEMBL3760523 0.79 DNM1 (0.44) DNM1CA1CA2CA12CA9
SCHEMBL6184056 0.79 KDM4E (0.46) DNM1CA1CA2CA12CA9
SCHEMBL3760526 0.79 DNM1 (0.44) DNM1CA1CA2CA12CA9
Hydrochloric Acid SCHEMBL17022764 0.78 DNM1 (0.47) DNM1CA1CA2CA12CA9
SCHEMBL9701323 0.77 SIGMAR1 (0.46) KDM4EKMT2ASMN1; SMN2MAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5132454-A Antihypoxic agents MEIJI SEIKA KAISHA, LTD. (JP) 1992-07-21 US disclosed
US-5066677-A Antihypoxic agents, treatment of disorders resulting from reduced oxygen supply to brain MEIJI SEIKA KAISHA, LTD. (JP) 1991-11-19 US disclosed
EP-0387074-A2 Novel oxamic acid compounds and pharmaceutical composition for use in improvement of damaged cerebral functions of brain MEIJI SEIKA KAISHA LTD. (JP) 1990-09-12 EP disclosed