Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.55 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.55 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566444 | 0.87 | MAPT (0.49) | TAS1R3TAS1R1TAS1R2PTK2MAPT | |
| SCHEMBL7573719 | 0.85 | TAS1R3 (0.44) | TAS1R3TAS1R1TAS1R2PTK2MAPT | |
| SCHEMBL7573613 | 0.85 | TAS1R3 (0.54) | TAS1R3TAS1R1TAS1R2PTK2SMN1; SMN2 | |
| SCHEMBL7566996 | 0.83 | TAS1R3 (0.49) | TAS1R3TAS1R1TAS1R2MAPTCYP1A2 | |
| SCHEMBL7998024 | 0.82 | MAPT (0.45) | TAS1R3TAS1R1TAS1R2PTK2MAPT | |
| SCHEMBL8013624 | 0.82 | MAPT (0.45) | TAS1R3TAS1R1TAS1R2PTK2MAPT | |
| SCHEMBL7568051 | 0.81 | TAS1R3 (0.51) | TAS1R3TAS1R1TAS1R2PTK2MAPT | |
| SCHEMBL7567031 | 0.80 | TAS1R3 (0.48) | TAS1R3TAS1R1TAS1R2MAPTCYP1A2 | |
| SCHEMBL7570875 | 0.80 | TAS1R3 (0.47) | TAS1R3TAS1R1TAS1R2MAPTCYP1A2 | |
| SCHEMBL7572166 | 0.79 | AOX1 (0.45) | TAS1R3TAS1R1TAS1R2PTK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |