Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOX1 | Q06278 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AKT3 | Q9Y243 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570655 | 0.87 | AOX1 (0.45) | AOX1TAS1R3TAS1R1TAS1R2PTK2 | |
| SCHEMBL7573719 | 0.85 | TAS1R3 (0.44) | TAS1R3TAS1R1TAS1R2HTTPTK2 | |
| SCHEMBL7568076 | 0.85 | AOX1 (0.45) | AOX1TAS1R3TAS1R1TAS1R2RXFP1 | |
| SCHEMBL7573613 | 0.84 | TAS1R3 (0.54) | AOX1TAS1R3TAS1R1TAS1R2HTT | |
| SCHEMBL7564792 | 0.79 | NPC1 (0.48) | TAS1R3TAS1R1PTK2ALDH1A1SMN1; SMN2 | |
| SCHEMBL8009922 | 0.79 | TAS1R3 (0.55) | TAS1R3TAS1R1TAS1R2HTTPTK2 | |
| SCHEMBL7567392 | 0.78 | CTSS (0.45) | TAS1R3TAS1R1TAS1R2PTK2HDAC1 | |
| SCHEMBL7566165 | 0.77 | TAS1R3 (0.39) | AOX1TAS1R3TAS1R1TAS1R2RXFP1 | |
| SCHEMBL8414087 | 0.75 | AOX1 (0.46) | AOX1TAS1R3TAS1R1TAS1R2RXFP1 | |
| SCHEMBL8013624 | 0.75 | MAPT (0.45) | TAS1R3TAS1R1TAS1R2HTTPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |