Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8013624 | 1.00 | MAPT (0.45) | MAPTCYP1A2CYP2C9CYP2C19TAS1R3 | |
| SCHEMBL7573719 | 0.88 | TAS1R3 (0.44) | MAPTCYP1A2CYP2C9CYP2C19TAS1R3 | |
| SCHEMBL7566444 | 0.85 | MAPT (0.49) | MAPTCYP1A2CYP2C9CYP2C19TAS1R3 | |
| SCHEMBL7566548 | 0.85 | MAPT (0.45) | MAPTCYP1A2CYP2C9CYP2C19TAS1R3 | |
| SCHEMBL7568879 | 0.85 | MAPT (0.45) | MAPTCYP1A2CYP2C9CYP2C19TAS1R3 | |
| SCHEMBL8009922 | 0.82 | TAS1R3 (0.55) | MAPTCYP1A2CYP2C9CYP2C19TAS1R3 | |
| SCHEMBL7568051 | 0.79 | TAS1R3 (0.51) | MAPTTAS1R3TAS1R1TAS1R2NQO2 | |
| SCHEMBL7572166 | 0.75 | AOX1 (0.45) | MAPTTAS1R3TAS1R1TAS1R2PTK2 | |
| SCHEMBL7570655 | 0.75 | AOX1 (0.45) | TAS1R3TAS1R1TAS1R2PTK2ALDH1A1 | |
| SCHEMBL2288888 | 0.74 | ALDH1A1 (0.71) | MAPTCYP1A2CYP2C9CYP2C19NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |