Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.49 |
| ▸ | NOS1 | P29475 | 2/20 | 0.49 |
| ▸ | NOS2 | P35228 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TPH1 | P17752 | 3/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4871525 | 0.84 | NOS3 (0.50) | NOS3NOS1NOS2CYP1A2LNPEP | |
| SCHEMBL5566353 | 0.79 | HSD17B10 (0.50) | NOS3NOS1NOS2CYP1A2SLC7A5 | |
| SCHEMBL31369944 | 0.79 | TPH1 (0.54) | TPH1CCR1CCR5CCR8SLC7A5 | |
| SCHEMBL8000728 | 0.78 | CYP1A2 (0.51) | CYP1A2SLC7A5HSD17B10LMNA | |
| SCHEMBL22775125 | 0.78 | CYP1A2 (0.51) | CYP1A2SLC7A5HSD17B10LMNA | |
| SCHEMBL24248055 | 0.77 | HSD17B10 (0.51) | CYP1A2SLC7A5HSD17B10 | |
| SCHEMBL15495937 | 0.77 | HSD17B10 (0.51) | CYP1A2SLC7A5HSD17B10LMNA | |
| SCHEMBL18995811 | 0.77 | HSD17B10 (0.51) | CYP1A2SLC7A5HSD17B10 | |
| SCHEMBL20278960 | 0.77 | NOS2 (0.49) | NOS3NOS1NOS2CCR1CCR5 | |
| SCHEMBL15743142 | 0.76 | NOS3 (0.56) | NOS3NOS1NOS2CYP1A2CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850316-A4 | CRYPTOPHYCINS FROM ABERRANT BIOSYNTHESIS | UNIV HAWAII (US) | 2000-08-23 | — | — | EP | disclosed |
| EP-0850316-A1 | CRYPTOPHYCINS FROM ABERRANT BIOSYNTHESIS | UNIVERSITY OF HAWAII (US) | 1998-07-01 | — | — | EP | disclosed |
| WO-1997008334-A1 | CRYPTOPHYCINS FROM ABERRANT BIOSYNTHESIS | UNIVERSITY OF HAWAII (US) | 1997-03-06 | — | — | WO | disclosed |