Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 15/20 | 0.54 |
| ▸ | TPH2 | Q8IWU9 | 2/20 | 0.48 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | CCR8 | P51685 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31369605 | 0.81 | TPH1 (0.58) | TPH1SLC7A5ITGB3ITGA2B | |
| SCHEMBL6168594 | 0.80 | TPH1 (0.68) | TPH1SLC7A5ITGB3ITGA2B | |
| SCHEMBL8009944 | 0.79 | NOS3 (0.49) | TPH1CCR1CCR5CCR8SLC7A5 | |
| SCHEMBL31369930 | 0.79 | SLC13A5 (0.54) | TPH1TPH2SLC7A5 | |
| SCHEMBL7345126 | 0.78 | TPH1 (0.63) | TPH1TPH2SLC7A5 | |
| SCHEMBL7345132 | 0.78 | TPH1 (0.63) | TPH1TPH2SLC7A5 | |
| SCHEMBL597743 | 0.78 | LDHA (0.71) | TPH1SLC7A5ITGB3ITGA2B | |
| SCHEMBL158667 | 0.78 | LDHA (0.71) | TPH1SLC7A5ITGB3ITGA2B | |
| SCHEMBL126195 | 0.78 | LDHA (0.71) | TPH1SLC7A5ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL16816865 | 0.77 | TPH1 (0.62) | TPH1TPH2SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | claimed |
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | BCAT1, BCAT2, PELP1 | TPH1 3558/4885TPH2 3547/4885CCR1 4146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.