Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 6/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.30 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.30 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8015115 | 0.94 | ENPP2 (0.34) | ENPP2MTNR1AMTNR1B | |
| SCHEMBL8005853 | 0.93 | ENPP2 (0.33) | ENPP2MTNR1AMTNR1B | |
| SCHEMBL8009964 | 0.90 | ENPP2 (0.34) | ENPP2BRD9 | |
| SCHEMBL8000689 | 0.85 | ENPP2 (0.32) | ENPP2BRD9 | |
| SCHEMBL8009965 | 0.79 | MTNR1A (0.36) | ENPP2MTNR1AMTNR1BABCB1BRD9 | |
| SCHEMBL8008368 | 0.79 | MTNR1A (0.36) | ENPP2MTNR1AMTNR1BABCB1BRD9 | |
| SCHEMBL8005747 | 0.78 | ALDH1A1 (0.37) | — | |
| SCHEMBL8008293 | 0.78 | MTNR1A (0.35) | ENPP2MTNR1AMTNR1BABCB1BRD9 | |
| SCHEMBL8005781 | 0.78 | ALDH1A1 (0.37) | — | |
| SCHEMBL10293193 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134987-A1 | DIFLUOROMETHYL-CONTAINING MACROCYCLIC COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2009-11-05 | — | — | WO | disclosed |