Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 18/20 | 0.71 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.65 |
| ▸ | RET | P07949 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8008969 | 0.98 | ADORA1 (0.71) | ADORA1SLC6A3RET | |
| SCHEMBL8006647 | 0.91 | ADORA1 (0.64) | ADORA1SLC6A3RET | |
| SCHEMBL8007650 | 0.89 | ADORA1 (0.56) | ADORA1SLC6A3RET | |
| SCHEMBL7997244 | 0.89 | ADORA1 (0.64) | ADORA1SLC6A3RET | |
| SCHEMBL8017303 | 0.86 | ADORA1 (0.73) | ADORA1SLC6A3 | |
| SCHEMBL12943378 | 0.84 | ADORA1 (0.73) | ADORA1SLC6A3 | |
| SCHEMBL8006531 | 0.83 | ALDH1A1 (0.54) | ADORA1SLC6A3RETMEN1PPARG | |
| SCHEMBL1177766 | 0.83 | ADORA1 (0.84) | ADORA1SLC6A3RET | |
| SCHEMBL8008774 | 0.82 | ADORA1 (0.54) | ADORA1SLC6A3 | |
| SCHEMBL7900475 | 0.81 | ADORA1 (0.78) | ADORA1SLC6A3RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009100827-A1 | CYCLOALKOXY-SUBSTITUTED 4-PHENYL-3,5-DICYANOPYRIDINES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-08-20 | — | — | WO | disclosed |